Abstract
This study deals with the relationship between elastase levels and catabolism of GPlb during the storage period in three types of platelet concentrates. Leucocyte contamination has been found to be associated with the release of a quantity of elastase, that is already detectable at day +1 of storage. Such an enzyme is able to promote hypercatabolism of GPlb and glycocalicin (i.e., the proteolytic split product of GPlb).
| Original language | Italian |
|---|---|
| Pages (from-to) | 264-267 |
| Number of pages | 4 |
| Journal | Trasfusione del Sangue |
| Volume | 44 |
| Issue number | 5 |
| Publication status | Published - 1999 |
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ASJC Scopus subject areas
- Hematology
- Immunology and Allergy
Cite this
Elastasi e modificazioni cataboliche della GPIb in concentrati piastrinici per uso trasfusionale. / Marson, P.; Ujka, F.; Zaninotto, M.; De Silvestro, G.; Steffan, A.; Fabris, F.; Plebani, M.; Ongaro, G.
In: Trasfusione del Sangue, Vol. 44, No. 5, 1999, p. 264-267.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Elastasi e modificazioni cataboliche della GPIb in concentrati piastrinici per uso trasfusionale
AU - Marson, P.
AU - Ujka, F.
AU - Zaninotto, M.
AU - De Silvestro, G.
AU - Steffan, A.
AU - Fabris, F.
AU - Plebani, M.
AU - Ongaro, G.
PY - 1999
Y1 - 1999
N2 - This study deals with the relationship between elastase levels and catabolism of GPlb during the storage period in three types of platelet concentrates. Leucocyte contamination has been found to be associated with the release of a quantity of elastase, that is already detectable at day +1 of storage. Such an enzyme is able to promote hypercatabolism of GPlb and glycocalicin (i.e., the proteolytic split product of GPlb).
AB - This study deals with the relationship between elastase levels and catabolism of GPlb during the storage period in three types of platelet concentrates. Leucocyte contamination has been found to be associated with the release of a quantity of elastase, that is already detectable at day +1 of storage. Such an enzyme is able to promote hypercatabolism of GPlb and glycocalicin (i.e., the proteolytic split product of GPlb).
KW - Elastase
KW - Glycocalicin
KW - GPIb
KW - Leucodepletion
KW - Platelet concentrates
UR - http://www.scopus.com/inward/record.url?scp=0033492034&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033492034&partnerID=8YFLogxK
M3 - Articolo
AN - SCOPUS:0033492034
VL - 44
SP - 264
EP - 267
JO - Trasfusione del Sangue
JF - Trasfusione del Sangue
SN - 0041-1787
IS - 5
ER -