Elastasi e modificazioni cataboliche della GPIb in concentrati piastrinici per uso trasfusionale

P. Marson; F. Ujka; M. Zaninotto; G. De Silvestro; A. Steffan; F. Fabris; M. Plebani; G. Ongaro

Elastasi e modificazioni cataboliche della GPIb in concentrati piastrinici per uso trasfusionale

Translated title of the contribution: Elastase and catabolic changes of GPIb in platelet concentrates for blood transfusion

P. Marson, F. Ujka, M. Zaninotto, G. De Silvestro, A. Steffan, F. Fabris, M. Plebani, G. Ongaro

Centro di Riferimento Oncologico

Research output: Contribution to journal › Article › peer-review

Abstract

This study deals with the relationship between elastase levels and catabolism of GPlb during the storage period in three types of platelet concentrates. Leucocyte contamination has been found to be associated with the release of a quantity of elastase, that is already detectable at day +1 of storage. Such an enzyme is able to promote hypercatabolism of GPlb and glycocalicin (i.e., the proteolytic split product of GPlb).

Translated title of the contribution	Elastase and catabolic changes of GPIb in platelet concentrates for blood transfusion
Original language	Italian
Pages (from-to)	264-267
Number of pages	4
Journal	Trasfusione del Sangue
Volume	44
Issue number	5
Publication status	Published - 1999

ASJC Scopus subject areas

Hematology
Immunology and Allergy

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title = "Elastasi e modificazioni cataboliche della GPIb in concentrati piastrinici per uso trasfusionale",

abstract = "This study deals with the relationship between elastase levels and catabolism of GPlb during the storage period in three types of platelet concentrates. Leucocyte contamination has been found to be associated with the release of a quantity of elastase, that is already detectable at day +1 of storage. Such an enzyme is able to promote hypercatabolism of GPlb and glycocalicin (i.e., the proteolytic split product of GPlb).",

keywords = "Elastase, Glycocalicin, GPIb, Leucodepletion, Platelet concentrates",

author = "P. Marson and F. Ujka and M. Zaninotto and {De Silvestro}, G. and A. Steffan and F. Fabris and M. Plebani and G. Ongaro",

year = "1999",

language = "Italian",

volume = "44",

pages = "264--267",

journal = "Trasfusione del Sangue",

issn = "0041-1787",

publisher = "SIMTI Servizi",

number = "5",

}

TY - JOUR

T1 - Elastasi e modificazioni cataboliche della GPIb in concentrati piastrinici per uso trasfusionale

AU - Marson, P.

AU - Ujka, F.

AU - Zaninotto, M.

AU - De Silvestro, G.

AU - Steffan, A.

AU - Fabris, F.

AU - Plebani, M.

AU - Ongaro, G.

PY - 1999

Y1 - 1999

N2 - This study deals with the relationship between elastase levels and catabolism of GPlb during the storage period in three types of platelet concentrates. Leucocyte contamination has been found to be associated with the release of a quantity of elastase, that is already detectable at day +1 of storage. Such an enzyme is able to promote hypercatabolism of GPlb and glycocalicin (i.e., the proteolytic split product of GPlb).

AB - This study deals with the relationship between elastase levels and catabolism of GPlb during the storage period in three types of platelet concentrates. Leucocyte contamination has been found to be associated with the release of a quantity of elastase, that is already detectable at day +1 of storage. Such an enzyme is able to promote hypercatabolism of GPlb and glycocalicin (i.e., the proteolytic split product of GPlb).

KW - Elastase

KW - Glycocalicin

KW - GPIb

KW - Leucodepletion

KW - Platelet concentrates

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M3 - Articolo

AN - SCOPUS:0033492034

VL - 44

SP - 264

EP - 267

JO - Trasfusione del Sangue

JF - Trasfusione del Sangue

SN - 0041-1787

IS - 5

ER -