Elastosonographic evaluation of thyroid nodules in acromegaly

Massimo Scacchi, Massimiliano Andrioli, Chiara Carzaniga, Giovanni Vitale, Mirella Moro, Luca Poggi, Francesca Pecori Giraldi, Letizia M. Fatti, Francesco Cavagnini

Research output: Contribution to journalArticlepeer-review


Objective: Ultrasound-elastography (US-E) appears to be a helpful tool for the diagnosis of thyroid cancer. In acromegaly, the prevalence of thyroid cancer is still debated. The aims of this study were to evaluate thyroid nodules in acromegaly and to establish the accuracy of US-E in providing information on their nature, using cytological analysis as a reference. Subjects and methods: US-E was applied to 90 nodules detected in 25 acromegalic patients and to 94 nodules found in 31 non-acromegalic goitrous subjects. The lesions were classified according to the elasticity scores (ES) as soft (ES 1-2) or hard (ES 3-4). Fine needle aspiration cytology could be performed in 60.8% of hard nodules in acromegalics and in 86.7% of hard nodules in controls. Results: The prevalence of hard nodules was significantly higher in the whole group of acromegalic patients than in controls (56.8 vs 16.0%, P

Original languageEnglish
Pages (from-to)607-613
Number of pages7
JournalEuropean Journal of Endocrinology
Issue number4
Publication statusPublished - 2009

ASJC Scopus subject areas

  • Endocrinology
  • Medicine(all)
  • Endocrinology, Diabetes and Metabolism


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