Abstract
We describe a 10-month-old boy diagnosed with X-linked hyper-IgM syndrome (XHIM) after suffering from life-threatening acute respiratory distress syndrome (ARDS) caused by Pneumocystis carinii pneumonia (PCP), although his previous clinical history and first level laboratory tests investigating immunological function did not indicate immunodeficiency. When the patient's overall condition was good, elective bone marrow transplantation from an HLA-matched older brother was performed successfully. We describe how correct diagnosis and successful treatment were made possible thanks to the involvement of a network of specialists.
| Original language | English |
|---|---|
| Pages (from-to) | 49-52 |
| Number of pages | 4 |
| Journal | Bone Marrow Transplantation |
| Volume | 30 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2002 |
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Keywords
- Acute respiratory distress syndrome
- Bone marrow transplantation
- Surfactant
- X-linked hyper-IgM syndrome
ASJC Scopus subject areas
- Hematology
- Transplantation
Cite this
Elective bone marrow transplantation in a child with X-linked hyper-IgM syndrome presenting with acute respiratory distress syndrome. / Leone, V.; Tommasini, A.; Andolina, M.; Runti, G.; De Vonderweid, U.; Campello, C.; Notarangelo, L. D.; Ventura, A.
In: Bone Marrow Transplantation, Vol. 30, No. 1, 2002, p. 49-52.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Elective bone marrow transplantation in a child with X-linked hyper-IgM syndrome presenting with acute respiratory distress syndrome
AU - Leone, V.
AU - Tommasini, A.
AU - Andolina, M.
AU - Runti, G.
AU - De Vonderweid, U.
AU - Campello, C.
AU - Notarangelo, L. D.
AU - Ventura, A.
PY - 2002
Y1 - 2002
N2 - We describe a 10-month-old boy diagnosed with X-linked hyper-IgM syndrome (XHIM) after suffering from life-threatening acute respiratory distress syndrome (ARDS) caused by Pneumocystis carinii pneumonia (PCP), although his previous clinical history and first level laboratory tests investigating immunological function did not indicate immunodeficiency. When the patient's overall condition was good, elective bone marrow transplantation from an HLA-matched older brother was performed successfully. We describe how correct diagnosis and successful treatment were made possible thanks to the involvement of a network of specialists.
AB - We describe a 10-month-old boy diagnosed with X-linked hyper-IgM syndrome (XHIM) after suffering from life-threatening acute respiratory distress syndrome (ARDS) caused by Pneumocystis carinii pneumonia (PCP), although his previous clinical history and first level laboratory tests investigating immunological function did not indicate immunodeficiency. When the patient's overall condition was good, elective bone marrow transplantation from an HLA-matched older brother was performed successfully. We describe how correct diagnosis and successful treatment were made possible thanks to the involvement of a network of specialists.
KW - Acute respiratory distress syndrome
KW - Bone marrow transplantation
KW - Surfactant
KW - X-linked hyper-IgM syndrome
UR - http://www.scopus.com/inward/record.url?scp=0036052122&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036052122&partnerID=8YFLogxK
U2 - 10.1038/sj.bmt.1703581
DO - 10.1038/sj.bmt.1703581
M3 - Article
VL - 30
SP - 49
EP - 52
JO - Bone Marrow Transplantation
JF - Bone Marrow Transplantation
SN - 0268-3369
IS - 1
ER -