Elective bone marrow transplantation in a child with X-linked hyper-IgM syndrome presenting with acute respiratory distress syndrome

V. Leone; A. Tommasini; M. Andolina; G. Runti; U. De Vonderweid; C. Campello; L. D. Notarangelo; A. Ventura

doi:10.1038/sj.bmt.1703581

Elective bone marrow transplantation in a child with X-linked hyper-IgM syndrome presenting with acute respiratory distress syndrome

V. Leone, A. Tommasini, M. Andolina, G. Runti, U. De Vonderweid, C. Campello, L. D. Notarangelo, A. Ventura

IRCCS pediatrico Burlo Garofolo

Research output: Contribution to journal › Article › peer-review

Abstract

We describe a 10-month-old boy diagnosed with X-linked hyper-IgM syndrome (XHIM) after suffering from life-threatening acute respiratory distress syndrome (ARDS) caused by Pneumocystis carinii pneumonia (PCP), although his previous clinical history and first level laboratory tests investigating immunological function did not indicate immunodeficiency. When the patient's overall condition was good, elective bone marrow transplantation from an HLA-matched older brother was performed successfully. We describe how correct diagnosis and successful treatment were made possible thanks to the involvement of a network of specialists.

Original language	English
Pages (from-to)	49-52
Number of pages	4
Journal	Bone Marrow Transplantation
Volume	30
Issue number	1
DOIs	https://doi.org/10.1038/sj.bmt.1703581
Publication status	Published - 2002

Keywords

Acute respiratory distress syndrome
Bone marrow transplantation
Surfactant
X-linked hyper-IgM syndrome

ASJC Scopus subject areas

Hematology
Transplantation

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Elective bone marrow transplantation in a child with X-linked hyper-IgM syndrome presenting with acute respiratory distress syndrome. / Leone, V.; Tommasini, A.; Andolina, M.; Runti, G.; De Vonderweid, U.; Campello, C.; Notarangelo, L. D.; Ventura, A.

In: Bone Marrow Transplantation, Vol. 30, No. 1, 2002, p. 49-52.

Research output: Contribution to journal › Article › peer-review

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