Elective bone marrow transplantation in a child with X-linked hyper-IgM syndrome presenting with acute respiratory distress syndrome

V. Leone, A. Tommasini, M. Andolina, G. Runti, U. De Vonderweid, C. Campello, L. D. Notarangelo, A. Ventura

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

We describe a 10-month-old boy diagnosed with X-linked hyper-IgM syndrome (XHIM) after suffering from life-threatening acute respiratory distress syndrome (ARDS) caused by Pneumocystis carinii pneumonia (PCP), although his previous clinical history and first level laboratory tests investigating immunological function did not indicate immunodeficiency. When the patient's overall condition was good, elective bone marrow transplantation from an HLA-matched older brother was performed successfully. We describe how correct diagnosis and successful treatment were made possible thanks to the involvement of a network of specialists.

Original languageEnglish
Pages (from-to)49-52
Number of pages4
JournalBone Marrow Transplantation
Volume30
Issue number1
DOIs
Publication statusPublished - 2002

Fingerprint

Type 1 Hyper-IgM Immunodeficiency Syndrome
Immunologic Tests
Pneumocystis Pneumonia
Adult Respiratory Distress Syndrome
Bone Marrow Transplantation
Siblings
Therapeutics

Keywords

  • Acute respiratory distress syndrome
  • Bone marrow transplantation
  • Surfactant
  • X-linked hyper-IgM syndrome

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Elective bone marrow transplantation in a child with X-linked hyper-IgM syndrome presenting with acute respiratory distress syndrome. / Leone, V.; Tommasini, A.; Andolina, M.; Runti, G.; De Vonderweid, U.; Campello, C.; Notarangelo, L. D.; Ventura, A.

In: Bone Marrow Transplantation, Vol. 30, No. 1, 2002, p. 49-52.

Research output: Contribution to journalArticle

Leone, V. ; Tommasini, A. ; Andolina, M. ; Runti, G. ; De Vonderweid, U. ; Campello, C. ; Notarangelo, L. D. ; Ventura, A. / Elective bone marrow transplantation in a child with X-linked hyper-IgM syndrome presenting with acute respiratory distress syndrome. In: Bone Marrow Transplantation. 2002 ; Vol. 30, No. 1. pp. 49-52.
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