Electrical alternation of the T-wave: Clinical and experimental evidence of its relationship with the sympathetic nervous system and with the long Q-T syndrome

Peter J. Schwartz, Alberto Malliani

Research output: Contribution to journalArticlepeer-review

Abstract

In a patient affected by the "long Q-T" syndrome we observed episodes of alternation of the T-wave associated with emotional or physical stresses. In anesthetized and vagotomized cats, we could reproduce both the lengthening of the Q-T interval and episodes of alternation of the T-wave by electrical stimulation of the left stellate ganglion. Our experiments provide further support on the relationships between the "long Q-T" syndrome and the sympathetic nervous system and indicate that alternation of the T-wave may depend on abrupt increases in the sympathetic discharge.

Original languageEnglish
Pages (from-to)45-50
Number of pages6
JournalAmerican Heart Journal
Volume89
Issue number1
DOIs
Publication statusPublished - 1975

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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