Electrical stimulation of denervated muscles: First results of a clinical study

Michaela Mödlin, Claudia Forstner, Christian Hofer, Winfried Mayr, Wolfgang Richter, Ugo Carraro, Feliciano Protasi, Helmut Kern

Research output: Contribution to journalArticlepeer-review

Abstract

To evaluate the effects of electrical stimulation on denervated muscles in spinal cord injured humans, the EU Project RISE was started in 2001. The aims of this project are: to design and build sufficient stimulators; to develop stimulation protocols by means of mathematical models, animal experiments, and practice in humans with denervated lower limbs; to develop examination methods and devices for evaluation of electrical stimulation training effects; and to acquire basic scientific knowledge on denervated and stimulated denervated muscle. In the clinical study 27 spinal cord injured individuals were included, furthermore 13 pilot patients participated. After a series of initial examinations they underwent an electrical stimulation program for their denervated lower limb muscles. Some of the patients have already follow up examinations. A marked increase of muscle mass and quality was observed, the trophic situation of the denervated lower limbs had improved obviously.

Original languageEnglish
Pages (from-to)203-206
Number of pages4
JournalArtificial Organs
Volume29
Issue number3
DOIs
Publication statusPublished - Mar 2005

Keywords

  • Computerized tomography scan
  • Denervated muscle
  • Electrical stimulation
  • Force measurement
  • Human
  • Spinal cord injury

ASJC Scopus subject areas

  • Biophysics

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