We report clinical and EEG features of four patients with merosin-negative congenital muscular dystrophy, diagnosed and followed at the Neurological Institute of Milan. In all the patients epileptiform EEG anomalies were recorded, located on occipital regions, increased during slow sleep; two cases had seizures (sporadic tonic-clonic during sleep in one, partial seizures with visual symptoms in one). None of the patients had structural cortical malformations detectable on MR. These findings indicate a cortical posterior involvement in merosin-negative congenital muscular dystrophy, in addition to the alterations in the white matter, typically detected in this disease.
|Translated title of the contribution||Electro-clinical features of four patients affected by merosin-negative congenital muscolar dystrophy|
|Number of pages||2|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - Oct 2002|
ASJC Scopus subject areas
- Clinical Neurology