Electrocardiogram waveforms for monitoring effectiveness of chest compression during cardiopulmonary resuscitation

Yongqin Li, Giuseppe Ristagno, Joe Bisera, Wanchun Tang, Qinkai Deng, Max Harry Weil

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

BACKGROUND: Newer guidelines address the importance of effective chest compressions, citing evidence that this primary intervention is usually suboptimally performed during cardiopulmonary resuscitation. We therefore sought a readily available option for monitoring the effectiveness of chest compressions, specifically using the electrocardiogram. METHODS AND RESULTS: Ventricular fibrillation was induced by coronary artery occlusion and untreated for 5 mins. Male domestic pigs weighing 40 ± 2 kg were randomized to optimal or suboptimal chest compressions after onset of ventricular fibrillation. Optimal depth of mechanical compression in six animals was defined as a decrease of 25% in anterior posterior diameter of the chest during compression. Suboptimal compression, also in six animals, was defined as a decrease of 17.5% in anterior posterior diameter. For each group, the chest compressions were maintained at a rate of 100 per min. After 3 mins of chest compression, defibrillation was attempted with a 150-J biphasic shock.All animals had return of spontaneous circulation after optimal compressions. This contrasted with suboptimal compressions, after which none of the animals had return of spontaneous circulation. Amplitude spectrum area values, representing the electrocardiographic amplitude frequency spectral area computed from conventional precordial leads, like coronary perfusion pressure and end tidal Pco2, were predictive of outcomes. CONCLUSION: The effectiveness of chest compressions was reflected in the amplitude spectrum area values. Accordingly, the amplitude spectrum area predictor may be incorporated in current automated external defibrillators to monitor and prompt the effectiveness of chest compression during cardiopulmonary resuscitation.

Original languageEnglish
Pages (from-to)211-215
Number of pages5
JournalCritical Care Medicine
Volume36
Issue number1
DOIs
Publication statusPublished - Jan 2008

Fingerprint

Cardiopulmonary Resuscitation
Electrocardiography
Thorax
Ventricular Fibrillation
Sus scrofa
Defibrillators
Coronary Occlusion
Shock
Coronary Vessels
Perfusion
Guidelines
Pressure

Keywords

  • Amplitude spectrum area
  • Cardiac arrest
  • Cardiopulmonary resuscitation
  • Chest compression
  • Electrocardiogram waveforms

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Electrocardiogram waveforms for monitoring effectiveness of chest compression during cardiopulmonary resuscitation. / Li, Yongqin; Ristagno, Giuseppe; Bisera, Joe; Tang, Wanchun; Deng, Qinkai; Weil, Max Harry.

In: Critical Care Medicine, Vol. 36, No. 1, 01.2008, p. 211-215.

Research output: Contribution to journalArticle

Li, Yongqin ; Ristagno, Giuseppe ; Bisera, Joe ; Tang, Wanchun ; Deng, Qinkai ; Weil, Max Harry. / Electrocardiogram waveforms for monitoring effectiveness of chest compression during cardiopulmonary resuscitation. In: Critical Care Medicine. 2008 ; Vol. 36, No. 1. pp. 211-215.
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