Electrocardiographic alterations and raised procalcitonin levels during anaphylactic shock

Antonio Mirijello; Maria Maddalena D'Errico; Pamela Piscitelli; Salvatore De Cosmo

doi:10.1136/bcr-2019-233521

Electrocardiographic alterations and raised procalcitonin levels during anaphylactic shock

Antonio Mirijello, Maria Maddalena D'Errico, Pamela Piscitelli, Salvatore De Cosmo

IRCCS Casa Sollievo della Sofferenza

Research output: Contribution to journal › Article › peer-review

Abstract

Anaphylaxis represents a systemic disease occurring after the exposure to an allergen. Drugs for the treatment of anaphylactic reactions (ie, corticosteroids and adrenalin) could induce autonomic alterations, such as tachycardia, hyperthermia, tachypnoea and leucocytosis. We describe the case of a 52-year-old woman presenting with a severe allergic reaction after the ingestion of amoxicillin-clavulanate. The occurrence of ECG alterations, laboratory abnormalities and procalcitonin (PCT) elevation will be discussed with particular emphasis on the possible misleading role of PCT during anaphylactic shock.

Original language	English
Article number	e233521
Journal	BMJ Case Reports
Volume	13
Issue number	1
DOIs	https://doi.org/10.1136/bcr-2019-233521
Publication status	Published - Jan 21 2020

Keywords

drugs and medicines
immunology
unwanted effects/adverse reactions

ASJC Scopus subject areas

Medicine(all)

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abstract = "Anaphylaxis represents a systemic disease occurring after the exposure to an allergen. Drugs for the treatment of anaphylactic reactions (ie, corticosteroids and adrenalin) could induce autonomic alterations, such as tachycardia, hyperthermia, tachypnoea and leucocytosis. We describe the case of a 52-year-old woman presenting with a severe allergic reaction after the ingestion of amoxicillin-clavulanate. The occurrence of ECG alterations, laboratory abnormalities and procalcitonin (PCT) elevation will be discussed with particular emphasis on the possible misleading role of PCT during anaphylactic shock.",

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