Electrocardiographic changes in HIV-infected, drug-experienced patients being treated with atazanavir

Nicola Gianotti, Monica Guffanti, Laura Galli, Alberto Margonato, Giulia Chiaravalli, Alba Bigoloni, Adriano Lazzarin, Antonella Castagna

Research output: Contribution to journalArticle

Abstract

The QRS interval of 56 out of 75 (74.7%) HIV-infected, drug-experienced patients (66.7% men) increased during treatment with boosted or unboosted atazanavir by a median 5 ms (interquartile range 0-9; P <0.0001); the PR and the QTc intervals did not change significantly. New asymptomatic bundle branch blocks were observed in four patients; one subject with a baseline first-degree atrioventricular block developed symptomatic bradyarrhythmia while receiving atenolol. The electrocardiographic monitoring of patients treated with atazanavir seems advisable.

Original languageEnglish
Pages (from-to)1648-1651
Number of pages4
JournalAIDS (London, England)
Volume21
Issue number12
DOIs
Publication statusPublished - Jul 2007

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

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