Abstract
Background: Cardiac resynchronization therapy (CRT) has proved to be very effective in improving morbidity and mortality in patients affected with severe congestive heart failure. Its efficacy has been shown to be greater in patients with left bundle branch block (LBBB). The aim of our study was to verify if newly proposed criteria for true LBBB identify patients with a better clinical and instrumental response to CRT. Methods: Between May 2007 and April 2011, 111 patients with left ventricular ejection fraction (LVEF) ≤ 35% and LBBB morphology received a CRT device and were divided into two groups according to QRS morphology. Group 1 (61 patients) consisted of patients with LBBB morphology; group 2 (50 patients) consisted of patients with LBBB. The primary endpoint was the utility of criteria for true LBBB to predict a composite endpoint of all-cause mortality and hospital admission with heart failure. The secondary endpoint was the utility of the same criteria to predict an absolute increase in LVEF ≥ 10%. Results: LBBB morphology and a dose of bisoprolol
| Original language | English |
|---|---|
| Pages (from-to) | 927-934 |
| Number of pages | 8 |
| Journal | PACE - Pacing and Clinical Electrophysiology |
| Volume | 35 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 2012 |
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Keywords
- CRT
- left bundle branch block
- morbidity
- mortality
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Electrocardiographic criteria of true left bundle branch block : A simple sign to predict a better clinical and instrumental response to CRT. / Mascioli, Giosuè; Padeletti, Luigi; Sassone, Biagio; Zecchin, Massimo; Lucca, Elena; Sacchi, Stefania; Boggian, Giulio; Tondo, Anna Ludovica; Belvito, Chiara; Bakhtadze, Nikoloz; Borrelli, Alessio; Sinagra, Gianfranco.
In: PACE - Pacing and Clinical Electrophysiology, Vol. 35, No. 8, 08.2012, p. 927-934.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Electrocardiographic criteria of true left bundle branch block
T2 - A simple sign to predict a better clinical and instrumental response to CRT
AU - Mascioli, Giosuè
AU - Padeletti, Luigi
AU - Sassone, Biagio
AU - Zecchin, Massimo
AU - Lucca, Elena
AU - Sacchi, Stefania
AU - Boggian, Giulio
AU - Tondo, Anna Ludovica
AU - Belvito, Chiara
AU - Bakhtadze, Nikoloz
AU - Borrelli, Alessio
AU - Sinagra, Gianfranco
PY - 2012/8
Y1 - 2012/8
N2 - Background: Cardiac resynchronization therapy (CRT) has proved to be very effective in improving morbidity and mortality in patients affected with severe congestive heart failure. Its efficacy has been shown to be greater in patients with left bundle branch block (LBBB). The aim of our study was to verify if newly proposed criteria for true LBBB identify patients with a better clinical and instrumental response to CRT. Methods: Between May 2007 and April 2011, 111 patients with left ventricular ejection fraction (LVEF) ≤ 35% and LBBB morphology received a CRT device and were divided into two groups according to QRS morphology. Group 1 (61 patients) consisted of patients with LBBB morphology; group 2 (50 patients) consisted of patients with LBBB. The primary endpoint was the utility of criteria for true LBBB to predict a composite endpoint of all-cause mortality and hospital admission with heart failure. The secondary endpoint was the utility of the same criteria to predict an absolute increase in LVEF ≥ 10%. Results: LBBB morphology and a dose of bisoprolol
AB - Background: Cardiac resynchronization therapy (CRT) has proved to be very effective in improving morbidity and mortality in patients affected with severe congestive heart failure. Its efficacy has been shown to be greater in patients with left bundle branch block (LBBB). The aim of our study was to verify if newly proposed criteria for true LBBB identify patients with a better clinical and instrumental response to CRT. Methods: Between May 2007 and April 2011, 111 patients with left ventricular ejection fraction (LVEF) ≤ 35% and LBBB morphology received a CRT device and were divided into two groups according to QRS morphology. Group 1 (61 patients) consisted of patients with LBBB morphology; group 2 (50 patients) consisted of patients with LBBB. The primary endpoint was the utility of criteria for true LBBB to predict a composite endpoint of all-cause mortality and hospital admission with heart failure. The secondary endpoint was the utility of the same criteria to predict an absolute increase in LVEF ≥ 10%. Results: LBBB morphology and a dose of bisoprolol
KW - CRT
KW - left bundle branch block
KW - morbidity
KW - mortality
UR - http://www.scopus.com/inward/record.url?scp=84864654480&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84864654480&partnerID=8YFLogxK
U2 - 10.1111/j.1540-8159.2012.03427.x
DO - 10.1111/j.1540-8159.2012.03427.x
M3 - Article
VL - 35
SP - 927
EP - 934
JO - PACE - Pacing and Clinical Electrophysiology
JF - PACE - Pacing and Clinical Electrophysiology
SN - 0147-8389
IS - 8
ER -