Electrocardiographic features of sudden unexpected death in epilepsy

Janice Y. Chyou, Daniel Friedman, Marina Cerrone, William Slater, Yu Guo, Daniel Taupin, Sean O'Rourke, Silvia G. Priori, Orrin Devinsky

Research output: Contribution to journalArticle

Abstract

Sudden unexpected death in epilepsy (SUDEP) is the most common cause of epilepsy-related mortality. We hypothesized that electrocardiography (ECG) features may distinguish SUDEP cases from living subjects with epilepsy. Using a matched case–control design, we compared ECG studies of 12 consecutive cases of SUDEP over 10 years and 22 epilepsy controls matched for age, sex, epilepsy type (focal, generalized, or unknown/mixed type), concomitant antiepileptic, and psychotropic drug classes. Conduction intervals and prevalence of abnormal ventricular conduction diagnosis (QRS ≥110 msec), abnormal ventricular conduction pattern (QRS

Original languageEnglish
Pages (from-to)e135-e139
JournalEpilepsia
Volume57
Issue number7
DOIs
Publication statusPublished - Jul 1 2016

Keywords

  • All epilepsy/seizures
  • Cardiac
  • Electrocardiogram
  • Risk factors in epidemiology
  • Sudden death

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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  • Cite this

    Chyou, J. Y., Friedman, D., Cerrone, M., Slater, W., Guo, Y., Taupin, D., O'Rourke, S., Priori, S. G., & Devinsky, O. (2016). Electrocardiographic features of sudden unexpected death in epilepsy. Epilepsia, 57(7), e135-e139. https://doi.org/10.1111/epi.13411