Electrocardiographic features of sudden unexpected death in epilepsy

Janice Y. Chyou, Daniel Friedman, Marina Cerrone, William Slater, Yu Guo, Daniel Taupin, Sean O'Rourke, Silvia G. Priori, Orrin Devinsky

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Sudden unexpected death in epilepsy (SUDEP) is the most common cause of epilepsy-related mortality. We hypothesized that electrocardiography (ECG) features may distinguish SUDEP cases from living subjects with epilepsy. Using a matched case–control design, we compared ECG studies of 12 consecutive cases of SUDEP over 10 years and 22 epilepsy controls matched for age, sex, epilepsy type (focal, generalized, or unknown/mixed type), concomitant antiepileptic, and psychotropic drug classes. Conduction intervals and prevalence of abnormal ventricular conduction diagnosis (QRS ≥110 msec), abnormal ventricular conduction pattern (QRS

Original languageEnglish
Pages (from-to)e135-e139
JournalEpilepsia
Volume57
Issue number7
DOIs
Publication statusPublished - Jul 1 2016

Fingerprint

Sudden Death
Epilepsy
Electrocardiography
Generalized Epilepsy
Partial Epilepsy
Psychotropic Drugs
Anticonvulsants
Mortality

Keywords

  • All epilepsy/seizures
  • Cardiac
  • Electrocardiogram
  • Risk factors in epidemiology
  • Sudden death

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Chyou, J. Y., Friedman, D., Cerrone, M., Slater, W., Guo, Y., Taupin, D., ... Devinsky, O. (2016). Electrocardiographic features of sudden unexpected death in epilepsy. Epilepsia, 57(7), e135-e139. https://doi.org/10.1111/epi.13411

Electrocardiographic features of sudden unexpected death in epilepsy. / Chyou, Janice Y.; Friedman, Daniel; Cerrone, Marina; Slater, William; Guo, Yu; Taupin, Daniel; O'Rourke, Sean; Priori, Silvia G.; Devinsky, Orrin.

In: Epilepsia, Vol. 57, No. 7, 01.07.2016, p. e135-e139.

Research output: Contribution to journalArticle

Chyou, JY, Friedman, D, Cerrone, M, Slater, W, Guo, Y, Taupin, D, O'Rourke, S, Priori, SG & Devinsky, O 2016, 'Electrocardiographic features of sudden unexpected death in epilepsy', Epilepsia, vol. 57, no. 7, pp. e135-e139. https://doi.org/10.1111/epi.13411
Chyou JY, Friedman D, Cerrone M, Slater W, Guo Y, Taupin D et al. Electrocardiographic features of sudden unexpected death in epilepsy. Epilepsia. 2016 Jul 1;57(7):e135-e139. https://doi.org/10.1111/epi.13411
Chyou, Janice Y. ; Friedman, Daniel ; Cerrone, Marina ; Slater, William ; Guo, Yu ; Taupin, Daniel ; O'Rourke, Sean ; Priori, Silvia G. ; Devinsky, Orrin. / Electrocardiographic features of sudden unexpected death in epilepsy. In: Epilepsia. 2016 ; Vol. 57, No. 7. pp. e135-e139.
@article{a9be66a955a64dfbac4090aed0701f5b,
title = "Electrocardiographic features of sudden unexpected death in epilepsy",
abstract = "Sudden unexpected death in epilepsy (SUDEP) is the most common cause of epilepsy-related mortality. We hypothesized that electrocardiography (ECG) features may distinguish SUDEP cases from living subjects with epilepsy. Using a matched case–control design, we compared ECG studies of 12 consecutive cases of SUDEP over 10 years and 22 epilepsy controls matched for age, sex, epilepsy type (focal, generalized, or unknown/mixed type), concomitant antiepileptic, and psychotropic drug classes. Conduction intervals and prevalence of abnormal ventricular conduction diagnosis (QRS ≥110 msec), abnormal ventricular conduction pattern (QRS",
keywords = "All epilepsy/seizures, Cardiac, Electrocardiogram, Risk factors in epidemiology, Sudden death",
author = "Chyou, {Janice Y.} and Daniel Friedman and Marina Cerrone and William Slater and Yu Guo and Daniel Taupin and Sean O'Rourke and Priori, {Silvia G.} and Orrin Devinsky",
year = "2016",
month = "7",
day = "1",
doi = "10.1111/epi.13411",
language = "English",
volume = "57",
pages = "e135--e139",
journal = "Epilepsia",
issn = "0013-9580",
publisher = "Blackwell Publishing Inc.",
number = "7",

}

TY - JOUR

T1 - Electrocardiographic features of sudden unexpected death in epilepsy

AU - Chyou, Janice Y.

AU - Friedman, Daniel

AU - Cerrone, Marina

AU - Slater, William

AU - Guo, Yu

AU - Taupin, Daniel

AU - O'Rourke, Sean

AU - Priori, Silvia G.

AU - Devinsky, Orrin

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Sudden unexpected death in epilepsy (SUDEP) is the most common cause of epilepsy-related mortality. We hypothesized that electrocardiography (ECG) features may distinguish SUDEP cases from living subjects with epilepsy. Using a matched case–control design, we compared ECG studies of 12 consecutive cases of SUDEP over 10 years and 22 epilepsy controls matched for age, sex, epilepsy type (focal, generalized, or unknown/mixed type), concomitant antiepileptic, and psychotropic drug classes. Conduction intervals and prevalence of abnormal ventricular conduction diagnosis (QRS ≥110 msec), abnormal ventricular conduction pattern (QRS

AB - Sudden unexpected death in epilepsy (SUDEP) is the most common cause of epilepsy-related mortality. We hypothesized that electrocardiography (ECG) features may distinguish SUDEP cases from living subjects with epilepsy. Using a matched case–control design, we compared ECG studies of 12 consecutive cases of SUDEP over 10 years and 22 epilepsy controls matched for age, sex, epilepsy type (focal, generalized, or unknown/mixed type), concomitant antiepileptic, and psychotropic drug classes. Conduction intervals and prevalence of abnormal ventricular conduction diagnosis (QRS ≥110 msec), abnormal ventricular conduction pattern (QRS

KW - All epilepsy/seizures

KW - Cardiac

KW - Electrocardiogram

KW - Risk factors in epidemiology

KW - Sudden death

UR - http://www.scopus.com/inward/record.url?scp=84977587904&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84977587904&partnerID=8YFLogxK

U2 - 10.1111/epi.13411

DO - 10.1111/epi.13411

M3 - Article

C2 - 27215589

AN - SCOPUS:84977587904

VL - 57

SP - e135-e139

JO - Epilepsia

JF - Epilepsia

SN - 0013-9580

IS - 7

ER -