Abstract
Sudden unexpected death in epilepsy (SUDEP) is the most common cause of epilepsy-related mortality. We hypothesized that electrocardiography (ECG) features may distinguish SUDEP cases from living subjects with epilepsy. Using a matched case–control design, we compared ECG studies of 12 consecutive cases of SUDEP over 10 years and 22 epilepsy controls matched for age, sex, epilepsy type (focal, generalized, or unknown/mixed type), concomitant antiepileptic, and psychotropic drug classes. Conduction intervals and prevalence of abnormal ventricular conduction diagnosis (QRS ≥110 msec), abnormal ventricular conduction pattern (QRS
| Original language | English |
|---|---|
| Pages (from-to) | e135-e139 |
| Journal | Epilepsia |
| Volume | 57 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 1 2016 |
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Keywords
- All epilepsy/seizures
- Cardiac
- Electrocardiogram
- Risk factors in epidemiology
- Sudden death
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
Cite this
Electrocardiographic features of sudden unexpected death in epilepsy. / Chyou, Janice Y.; Friedman, Daniel; Cerrone, Marina; Slater, William; Guo, Yu; Taupin, Daniel; O'Rourke, Sean; Priori, Silvia G.; Devinsky, Orrin.
In: Epilepsia, Vol. 57, No. 7, 01.07.2016, p. e135-e139.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Electrocardiographic features of sudden unexpected death in epilepsy
AU - Chyou, Janice Y.
AU - Friedman, Daniel
AU - Cerrone, Marina
AU - Slater, William
AU - Guo, Yu
AU - Taupin, Daniel
AU - O'Rourke, Sean
AU - Priori, Silvia G.
AU - Devinsky, Orrin
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Sudden unexpected death in epilepsy (SUDEP) is the most common cause of epilepsy-related mortality. We hypothesized that electrocardiography (ECG) features may distinguish SUDEP cases from living subjects with epilepsy. Using a matched case–control design, we compared ECG studies of 12 consecutive cases of SUDEP over 10 years and 22 epilepsy controls matched for age, sex, epilepsy type (focal, generalized, or unknown/mixed type), concomitant antiepileptic, and psychotropic drug classes. Conduction intervals and prevalence of abnormal ventricular conduction diagnosis (QRS ≥110 msec), abnormal ventricular conduction pattern (QRS
AB - Sudden unexpected death in epilepsy (SUDEP) is the most common cause of epilepsy-related mortality. We hypothesized that electrocardiography (ECG) features may distinguish SUDEP cases from living subjects with epilepsy. Using a matched case–control design, we compared ECG studies of 12 consecutive cases of SUDEP over 10 years and 22 epilepsy controls matched for age, sex, epilepsy type (focal, generalized, or unknown/mixed type), concomitant antiepileptic, and psychotropic drug classes. Conduction intervals and prevalence of abnormal ventricular conduction diagnosis (QRS ≥110 msec), abnormal ventricular conduction pattern (QRS
KW - All epilepsy/seizures
KW - Cardiac
KW - Electrocardiogram
KW - Risk factors in epidemiology
KW - Sudden death
UR - http://www.scopus.com/inward/record.url?scp=84977587904&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84977587904&partnerID=8YFLogxK
U2 - 10.1111/epi.13411
DO - 10.1111/epi.13411
M3 - Article
C2 - 27215589
AN - SCOPUS:84977587904
VL - 57
SP - e135-e139
JO - Epilepsia
JF - Epilepsia
SN - 0013-9580
IS - 7
ER -