Electrocardiographic features of sudden unexpected death in epilepsy

Janice Y. Chyou; Daniel Friedman; Marina Cerrone; William Slater; Yu Guo; Daniel Taupin; Sean O'Rourke; Silvia G. Priori; Orrin Devinsky

doi:10.1111/epi.13411

Electrocardiographic features of sudden unexpected death in epilepsy

Janice Y. Chyou, Daniel Friedman, Marina Cerrone, William Slater, Yu Guo, Daniel Taupin, Sean O'Rourke, Silvia G. Priori, Orrin Devinsky

Istituti Clinici Scientifici Maugeri Spa – Società Benefit

Research output: Contribution to journal › Article

Abstract

Sudden unexpected death in epilepsy (SUDEP) is the most common cause of epilepsy-related mortality. We hypothesized that electrocardiography (ECG) features may distinguish SUDEP cases from living subjects with epilepsy. Using a matched case–control design, we compared ECG studies of 12 consecutive cases of SUDEP over 10 years and 22 epilepsy controls matched for age, sex, epilepsy type (focal, generalized, or unknown/mixed type), concomitant antiepileptic, and psychotropic drug classes. Conduction intervals and prevalence of abnormal ventricular conduction diagnosis (QRS ≥110 msec), abnormal ventricular conduction pattern (QRS

Original language	English
Pages (from-to)	e135-e139
Journal	Epilepsia
Volume	57
Issue number	7
DOIs	https://doi.org/10.1111/epi.13411
Publication status	Published - Jul 1 2016

Keywords

All epilepsy/seizures
Cardiac
Electrocardiogram
Risk factors in epidemiology
Sudden death

ASJC Scopus subject areas

Clinical Neurology
Neurology

Access to Document

10.1111/epi.13411

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Chyou, J. Y., Friedman, D., Cerrone, M., Slater, W., Guo, Y., Taupin, D., O'Rourke, S., Priori, S. G., & Devinsky, O. (2016). Electrocardiographic features of sudden unexpected death in epilepsy. Epilepsia, 57(7), e135-e139. https://doi.org/10.1111/epi.13411

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