Electrochemotherapy as a new therapeutic strategy in advanced Merkel cell carcinoma of head and neck region

Research output: Contribution to journalArticle

Abstract

Background. Merkel Cell Carcinoma (MCC) is a rare and aggressive tumour, arising from a cutaneous mechanoceptor cell located in the basal layer of epidermis, with poor prognosis. The treatment of choice for the initial stage of the disease is surgery and/or radiotherapy. The treatment of recurrent or advanced disease is still controversial. Case report. We report a case of 84 years old woman with a recurrent MCC of the chin treated with electrochemotherapy (ECT). During the period of 20 months, four sessions of ECT were employed, which resulted in an objective response of the tumour and good quality of residual life. Conclusions. Our case shows the effectiveness of ECT in the treatment of locally advanced MCC of the head and neck region in a patient not suitable for standard therapeutic options.

Original languageEnglish
Pages (from-to)366-369
Number of pages4
JournalRadiology and Oncology
Volume47
Issue number4
DOIs
Publication statusPublished - 2013

Keywords

  • Electrochemotherapy
  • Head and neck cancer
  • Merkel cell carcinoma
  • Palliative treatment

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

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