TY - JOUR
T1 - Electrochemotherapy for the Treatment of Multiple Melanomas in a Horse
AU - Spugnini, Enrico P.
AU - D' Alterio, Gian Lorenzo
AU - Dotsinsky, Ivan
AU - Mudrov, Tzvetan
AU - Dragonetti, Emanuele
AU - Murace, Raffaele
AU - Citro, Gennaro
AU - Baldi, Alfonso
PY - 2011/8
Y1 - 2011/8
N2 - A 22-year-old Camargue mare was referred for showing signs of discomfort during chewing, building up of food in the mouth, and foul odor from the mouth. On physical examination, the mare presented bilateral pigmented labial masses affecting the upper and lower lips, more in the form of plaques at the mucocutaneous junction as well as multiple perivulvar and perianal lumps. The skin lesions were biopsied for histopathologic examination and the clinical suspect of melanoma was confirmed. The owner elected the lesions to be treated with electrochemotherapy using the drug cisplatin. After two sessions, the nodules were shrunk by 50% and the horse's ability to feed normally was restored: at that time, the owner had the treatment discontinued because of financial issues. The horse is still in partial remission after 1 year from the end of the treatment. Electrochemotherapy can be successfully used to palliate large melanomas in horses.
AB - A 22-year-old Camargue mare was referred for showing signs of discomfort during chewing, building up of food in the mouth, and foul odor from the mouth. On physical examination, the mare presented bilateral pigmented labial masses affecting the upper and lower lips, more in the form of plaques at the mucocutaneous junction as well as multiple perivulvar and perianal lumps. The skin lesions were biopsied for histopathologic examination and the clinical suspect of melanoma was confirmed. The owner elected the lesions to be treated with electrochemotherapy using the drug cisplatin. After two sessions, the nodules were shrunk by 50% and the horse's ability to feed normally was restored: at that time, the owner had the treatment discontinued because of financial issues. The horse is still in partial remission after 1 year from the end of the treatment. Electrochemotherapy can be successfully used to palliate large melanomas in horses.
KW - Biphasic pulses
KW - Cisplatin
KW - Horse
KW - Melanoma
KW - Portable equipment
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U2 - 10.1016/j.jevs.2011.01.009
DO - 10.1016/j.jevs.2011.01.009
M3 - Article
AN - SCOPUS:79960792518
VL - 31
SP - 430
EP - 433
JO - Journal of Equine Veterinary Science
JF - Journal of Equine Veterinary Science
SN - 0737-0806
IS - 8
ER -