Electrochemotherapy of a multirecurrent dermatofibrosarcoma protuberans of the orbital margin: A case report

Antonio Bonadies, Fulvia Elia, Francesco Maria Solivetti, Antonello Vidiri, Luca Muscardin, Stefania Bucher

Research output: Contribution to journalArticlepeer-review


Dermatofibrosarcoma protuberans (DFSP) is an uncommon cutaneous sarcoma with high recurrence rate. Radical surgery is the treatment of choice, although in cosmetically-sensitive areas such as the head and neck, this option is often not pursued. Electrochemotherapy (ECT) is a minimal invasive anti-tumor modality which is increasingly being used to treat skin metastases from different malignancies. A 31-year-old woman presented with subcutaneous local multirecurring DFSP located at the proximal end of the left eyebrow. ECT was offered as a palliative treatment to avoid radical disfiguring surgery. Two days following ECT, the patient was discharged in good general health. Partial tumor regression was appreciable at two months' follow-up by ultrasound and magnetic resonance imaging. At six months, residual fibrotic tissue was observed; at three years, no evidence of the tumour was detected. In our case, ECT achieved good local tumor control with excellent cosmetic results, preserving the patient's quality of life.

Original languageEnglish
Pages (from-to)6121-6126
Number of pages6
JournalAnticancer Research
Issue number11
Publication statusPublished - Nov 1 2015


  • Dermatofibrosarcoma protuberans
  • Electrochemotherapy
  • Ocular area
  • Quality of life

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)


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