Electromagnetically enhanced coating of a sintered titanium grid with human SAOS-2 osteoblasts and extracellular matrix

Lorenzo Fassina, Enrica Saino, Livia Visai, Giovanni Magenes

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The surface modification of a sintered titanium scaffold could play an important role in bone tissue engineering. In this study we have followed a biomimetic strategy where electromagnetically stimulated human SAOS-2 osteoblasts proliferated and built their extracellular matrix on a sintered titanium grid. In comparison with control conditions (standard cell culture incubator, where no electromagnetic stimulus was detectable), the electromagnetic stimulus (magnetic field, 2 mT; frequency, 75 Hz) increased the cell proliferation and the surface coating with decorin, osteopontin, and type-I collagen. The electromagnetic stimulus aimed at obtaining a better surface coating of the sintered titanium grid in terms of cell colonization and bone matrix. The superficially modified biomaterial could be used, in clinical applications, as an implant for bone repair.

Original languageEnglish
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"
Pages3582-3585
Number of pages4
Publication statusPublished - 2008
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: Aug 20 2008Aug 25 2008

Other

Other30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
CountryCanada
CityVancouver, BC
Period8/20/088/25/08

Fingerprint

Electromagnetic Phenomena
Osteoblasts
Titanium
Extracellular Matrix
Bone
Coatings
Decorin
Bone and Bones
Incubators
Biomimetics
Bone Matrix
Osteopontin
Cell proliferation
Biocompatible Materials
Magnetic Fields
Tissue Engineering
Scaffolds (biology)
Collagen Type I
Tissue engineering
Cell culture

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Fassina, L., Saino, E., Visai, L., & Magenes, G. (2008). Electromagnetically enhanced coating of a sintered titanium grid with human SAOS-2 osteoblasts and extracellular matrix. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology" (pp. 3582-3585). [4649980]

Electromagnetically enhanced coating of a sintered titanium grid with human SAOS-2 osteoblasts and extracellular matrix. / Fassina, Lorenzo; Saino, Enrica; Visai, Livia; Magenes, Giovanni.

Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology". 2008. p. 3582-3585 4649980.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fassina, L, Saino, E, Visai, L & Magenes, G 2008, Electromagnetically enhanced coating of a sintered titanium grid with human SAOS-2 osteoblasts and extracellular matrix. in Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"., 4649980, pp. 3582-3585, 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08, Vancouver, BC, Canada, 8/20/08.
Fassina L, Saino E, Visai L, Magenes G. Electromagnetically enhanced coating of a sintered titanium grid with human SAOS-2 osteoblasts and extracellular matrix. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology". 2008. p. 3582-3585. 4649980
Fassina, Lorenzo ; Saino, Enrica ; Visai, Livia ; Magenes, Giovanni. / Electromagnetically enhanced coating of a sintered titanium grid with human SAOS-2 osteoblasts and extracellular matrix. Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology". 2008. pp. 3582-3585
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