This study describes the occurrence of carpal tunnel syndrome in three patients (two men and one woman) chronically treated (for more than three years) with beta-blocker agents (propranolol in two patients, 120 mg/day and 160 mg/day; pindolol in the other, 15 mg/day). All secondary causes of carpal tunnel syndrome were excluded after clinical and instrumental investigation (including nuclear magnetic resonance at the wrist). Other conditions (latent peripheral neuropathy, e.g., diabetic neuropathy, and cervical arthritis) that might predispose to carpal tunnel syndrome (double-crush syndrome) were also excluded. After drug suspension, the patients' symptomatologic and electromyographic improvement led us to conclude that the carpal tunnel syndrome was caused by beta-blocker therapy.
|Number of pages||6|
|Journal||Current Therapeutic Research|
|Publication status||Published - 1990|
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