Ocular movements of 15 epileptic patients treated with CBZ were recorded twice during the same morning, before and 2 hours after the administration of the drug. Each recording session was preceded by the determination of drug concentration in blood and by a neurologic evaluation of the pt. Pursuit movements, saccades and spontaneous nystagmus were recorded by electrooculographic method. A reduction of the pursuit gain (6 pts), of the saccade accuracy (10 pts) and velocity (the automatic analysis is still in progress) were found to be directly correlated with an increase of CBZ plasma levels, within a range of 4.9 μg/ml to 13.9 μg/ml.
|Translated title of the contribution||Electrooculographic evaluation of CBZ side effects|
|Number of pages||2|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - 1984|
ASJC Scopus subject areas
- Clinical Neurology