Electrophysiological and immunogenetic findings in recurrent monosymptomatic-type hypersomnia: A study of two unrelated Italian cases

R. Manni, M. Martinetti, M. T. Ratti, A. Tartara

Research output: Contribution to journalArticle


MSLT and immunogenetic findings in two unrelated Italian subjects with recurrent monosymptomatic hypersomnia are reported. In both patients MSLT documented a markedly increased daytime sleep propensity during the attacks without augmented REM sleep pressure. Both patients share the same HLA haplotype (HLA-DR1, DQ1) which has been found in Kleine-Levin syndrome. This makes these subtypes of recurrent hypersomnia indistinguishable one from the other, under the immunogenetic profile, but permits differentiation from narcolepsy which is HLA-DR2, DQ1 closely linked.

Original languageEnglish
Pages (from-to)293-295
Number of pages3
JournalActa Neurologica Scandinavica
Issue number4
Publication statusPublished - 1993



  • immunogenetic findings
  • MSLT
  • recurrent hypersomnia

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this