Abstract
EEGs, brainstem auditory evoked potentials (BAEPs) and auditory event-related potentials (ERPs) were recorded from 33 individuals infected with the human immunodeficiency virus, type 1 (HIV1+ patients: 13 CDC Class II or III; 20 Class IV). All were neurologically asymptomatic, non-demented, and has a past history of intravenous drug abuse. Sixteen age- and sex-matched normals and 10 HIV1- former drug addicts served as controls. Half of the HIV1+ and HIV1- subjects displayed mild EEG anomalies and, except for one HIV+ patient, BAEPs were normal in both groups. ERPs were normal in all HIV1- subjects but anomalous (longer latencies of components P2, N2, P3; reduced amplitude of P3) in 9 HIV1+ patients (27%), the incidence of such anomalies being higher for Class IV than Class II/III patients. Auditory ERPs proved the most sensitive and specific of these electrophysiological procedures in detecting subclinical central nervous system involvement in HIV1 infection.
Original language | English |
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Pages (from-to) | 47-51 |
Number of pages | 5 |
Journal | Acta Neurologica Scandinavica |
Volume | 87 |
Issue number | 1 |
Publication status | Published - 1993 |
Keywords
- BAEPs
- Drug addiction
- EEGs
- Electrophysiology
- ERPs
- HIV1 infection
ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)