Electrophysiology of the corticomotoneurone pathways in patients with movement disorders.

P. D. Thompson, J. P. Dick, B. L. Day, J. C. Rothwell, A. Berardelli, T. Kachi, C. D. Marsden

Research output: Contribution to journalArticlepeer-review


The corticomotoneurone pathways were examined in 21 patients with movement disorders, using the technique of percutaneous electrical stimulation of the motor cortex. Conduction in these pathways was assessed by measuring the latency to onset of electromyographic activity in the muscles of the upper limb after cortical stimulation. In all patients [five with primary (idiopathic) torsion dystonia and two with secondary (symptomatic) hemidystonia, seven with Huntington's disease, four with essential tremor, and three with Parkinson's disease] central motor conduction was normal. This and other evidence suggests that the origin of the disorder of movement in these conditions lies in the delivery of abnormal motor commands to a normal corticomotoneuronal system.

Original languageEnglish
Pages (from-to)113-117
Number of pages5
JournalMovement Disorders
Issue number2
Publication statusPublished - 1986

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


Dive into the research topics of 'Electrophysiology of the corticomotoneurone pathways in patients with movement disorders.'. Together they form a unique fingerprint.

Cite this