Elevated intraocular pressure in patients with acromegaly

Luciano Quaranta, Ivano Riva, Gherardo Mazziotti, Teresa Porcelli, Irene Floriani, Andreas Katsanos, Andrea Giustina, Anastasios G P Konstas

Research output: Contribution to journalArticlepeer-review


Purpose: To evaluate central corneal thickness (CCT) and intraocular pressure (IOP) in a cohort of acromegalic patients, and to correlate CCT with serum levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). Methods: Consecutive patients affected by acromegaly underwent a comprehensive endocrinological and ophthalmological evaluation, including serum GH and IGF-1 levels, CCT measured with ultrasonic pachymetry and IOP assessed with Goldmann applanation tonometry. Results: Fourteen patients with acromegaly and 28 healthy controls were included in the study. Acromegalic patients had a statistically higher median CCT (570 μm [range 551.5-638] vs 542.7 μm [range 461.5-610]; p

Original languageEnglish
Pages (from-to)1133-1139
Number of pages7
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Issue number7
Publication statusPublished - 2014


  • Acromegal
  • Central corneal thickness
  • Glaucoma
  • Goldmann applanation tonometry
  • Intraocular pressure

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience
  • Medicine(all)


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