Abstract
Transforming growth factor β (TGF-β) is an immunosuppressive cytokine which can induce immunoglobulin A (IgA) switch and Epstein-Barr virus (EBV) replication in latently infected cells. Here we report elevated serum levels of TGF-β in various EBV-associated diseases correlating positively with EBV- specific IgA titers and negatively with IgM titers, suggesting a role for this cytokine in the pathogenesis of these diseases.
Original language | English |
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Pages (from-to) | 2443-2446 |
Number of pages | 4 |
Journal | Journal of Virology |
Volume | 74 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2000 |
ASJC Scopus subject areas
- Immunology