Elevations in plasma growth hormone concentration after luteinizing hormone releasing hormone (LRH) in patients with active acromegaly

G. Faglia, P. Beck-Peccoz, P. Travaglini, A. Paracchi, A. Spada, A. Lewin

Research output: Contribution to journalArticlepeer-review

Abstract

Out of 16 patients with active acromegaly, 6 increased plasma GH after LRH and 10 after TRH administration. These increases were unrelated to basal plasma GH levels and to plasma GH responses to insulin and arginine. Two patients who responded to LRH did not increase plasma GH after TRH. It is suggested that these GH responses to non specific releasing hormones may be due either to an alteration of the cellular membrane or to an extra pituitary action, probably at a hypothalamic locus, of these peptides.

Original languageEnglish
Pages (from-to)338-340
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume37
Issue number2
Publication statusPublished - 1973

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

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