ELISA antibodies to cytomegalovirus in pregnant patients: Prevalence in and correlation with spontaneous abortion

M. Luerti, A. Santini, O. Bernini, M. Castiglioni, M. C. Ragni

Research output: Contribution to journalArticle

Abstract

Prevalence of seroimmunity to cytomegalovirus (CMV) infection was tested by detecting ELISA IgG antibodies in 230 pregnant subjects from low socioeconomic backgrounds. Seroimmunity increased from 64.3% to 92.0% between the ages 15-20 and 35-40. Furthermore, ELISA IgM antibodies were detected during hospitalization in a group of 56 women whose pregnancies ended in spontaneous abortion and in a paired matched-control group. The overall percentage of IgM-positive reactions was 5.35% in the group with abortion. The percentage for only second trimester abortions amounted to 18.75%. There was no IgM-positive reaction in the control group.

Original languageEnglish
Pages (from-to)181-183
Number of pages3
JournalBiological Research in Pregnancy and Perinatology
Volume4
Issue number4
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Medicine(all)

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