Embryonal rhabdomyosarcoma of the orbit in a liver transplant recipient

Matteo Cescon, Gian Luca Grazi, Roberto Assietti, Alberto Scanni, Franco Frigerio, Francesca Sparacio, Giorgio Ercolani, Antonino Cavallari

Research output: Contribution to journalArticlepeer-review


Although an increased incidence of de novo malignancies is reported in transplant recipients, rhabdomyosarcoma, an aggressive mesenchymal tumor typical of childhood, is not considered a neoplasm commonly related to immunosuppression. A 21-year-old woman presented with unilateral diplopia and proptosis 16 months after liver transplantation for fulminant hepatic failure. A tumoral mass originating from the medial rectus muscle was partially removed and diagnosed as being an embryonal rhabdomyosarcoma. Since the patient refused complete orbital excision, one course of radiotherapy and six courses of chemotherapy were administered, while immunosuppression was re-modulated, without interruption of the administration of cyclosporine. Complete control of tumor growth was achieved, while no alterations of graft function were observed throughout the treatment period.

Original languageEnglish
Pages (from-to)437-440
Number of pages4
JournalTransplant International
Issue number6
Publication statusPublished - Jun 1 2003


  • Embryonal
  • Liver transplantation
  • Rhabdomyosarcoma

ASJC Scopus subject areas

  • Transplantation


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