Emergence in Klebsiella pneumoniae and Enterobacter cloacae Clinical Isolates of the VIM-4 Metallo-β-Lactamase Encoded by a Conjugative Plasmid

Francesco Luzzaro, Jean Denis Docquier, Céline Colinon, Andrea Endimiani, Gianluigi Lombardi, Gianfranco Amicosante, Gian Maria Rossolini, Antonio Toniolo

Research output: Contribution to journalArticlepeer-review

Abstract

Resistance to carbapenems is an emerging problem among gram-negative hospital pathogens. A transferable plasmid encoding the VIM-4 metallo-β-lactamase was detected in isolates of Klebsiella pneumoniae and Enterobacter cloacae obtained from a single patient under carbapenem therapy. Thus, enterobacteria appear to increasingly contribute to the spread of VIM-type enzymes.

Original languageEnglish
Pages (from-to)648-650
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume48
Issue number2
DOIs
Publication statusPublished - Feb 2004

ASJC Scopus subject areas

  • Pharmacology (medical)

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