Emergence of divergent enterovirus (EV) D68 sub-clade D1 strains, northern Italy, September to October 2018

Laura Pellegrinelli, Federica Giardina, Giovanna Lunghi, Sara Colonia Uceda Renteria, Letizia Greco, Alice Fratini, Cristina Galli, Antonio Piralla, Sandro Binda, Elena Pariani, Fausto Baldanti

Research output: Contribution to journalArticle

Abstract

Between September and October 2018, an enterovirus D68 (EV-D68) outbreak occurred in patients hospitalised with severe acute respiratory infection in northern Italy; 21 laboratory-confirmed cases were reported. Phylogenetic analysis revealed that 16/20 of the EV-D68 sequences belonged to a divergent group within the sub-clade D1. Since its upsurge, EV-D68 has undergone rapid evolution with the emergence of new viral variants, emphasising the need for molecular surveillance that include outpatients with respiratory illness.

Keywords

  • enterovirus D68, respiratory infection, phylogenetic analysis, molecular surveillance
  • EV-D68

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health
  • Virology

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