Emergence of quinolone-resistant Shigella flexneri in Italy (March 2017)

Marta Zatta, Stefano Di Bella, Marina Busetti, Valeria Michelacci, Slawomir Owczarek, Ida Luzzi, Roberto Luzzati

Research output: Contribution to journalArticle

Abstract

In March 2017, a 45-year-old Italian man who has sex with men was admitted to the Infectious Diseases Department of Trieste Hospital (northeast Italy), because of fever, abdominal pain and dysentery. The patient had neither foreign travel history nor sexual contact with non-Italian partners. Stool cultures grew multidrug-resistant Shigella flexneri (resistant to ampicillin, chloramphenicol, streptomycin, tetracycline, trimethoprim, amoxicillin/clavulanic acid and ciprofloxacin) and whole genome sequencing detailed the resistance features. The phylogenetic analysis showed that the strain was unrelated to any previously reported strain. The patient was treated successfully with ceftriaxone. We hereby report the first case of locally-acquired, multidrug-resistant S. flexneri infection in Italy and also the emergence of a new clone.

Original languageEnglish
Pages (from-to)1123-1126
Number of pages4
JournalInternational Journal of STD and AIDS
Volume29
Issue number11
DOIs
Publication statusPublished - Oct 1 2018

Keywords

  • antibiotic resistance
  • bacterial disease
  • Epidemiology
  • Shigella
  • uinolone resistance

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Pharmacology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Emergence of quinolone-resistant Shigella flexneri in Italy (March 2017)'. Together they form a unique fingerprint.

  • Cite this

    Zatta, M., Di Bella, S., Busetti, M., Michelacci, V., Owczarek, S., Luzzi, I., & Luzzati, R. (2018). Emergence of quinolone-resistant Shigella flexneri in Italy (March 2017). International Journal of STD and AIDS, 29(11), 1123-1126. https://doi.org/10.1177/0956462418769805