Abstract
Purpose of Review: Drug resistance, particularly through multidrug-resistant tuberculosis (TB) and extensively drug-resistant TB strains, poses a real threat to TB control worldwide. Recent reports from the WHO and the International Union Against Tuberculosis and Lung Disease demonstrate that the emerging epidemic of drug-resistant TB is a global problem, although emphasis has been placed on several 'hot spots' because of lack of good global data. Recent Findings: The present article is aimed at reviewing the available information on drug-resistant TB with special focus on the features of the epidemic in Europe, Russia, Latin America, Asia and specifically China, and to discuss the global perspectives related to drug-resistant TB control and care. Summary: Drug-resistant TB originates from different human errors, including misuse of anti-TB drugs and other reasons related to prescribers, patients and drug producers. Although there is an urgent need for new drugs, a sound public health approach is necessary for their introduction in clinical treatment settings to prevent/avoid creating additional resistance, as has already been observed for first and second-line anti-TB drugs in many settings.
| Original language | English |
|---|---|
| Pages (from-to) | 171-179 |
| Number of pages | 9 |
| Journal | Current Opinion in Pulmonary Medicine |
| Volume | 16 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - May 2010 |
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Keywords
- Asia
- China
- Drug-resistant tuberculosis
- Europe
- Extensively drug-resistant tuberculosis
- Latin America
- Multidrug-resistant tuberculosis
- Russia
- Tuberculosis
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
Emerging epidemic of drug-resistant tuberculosis in Europe, Russia, China, South America and Asia : Current status and global perspectives. / Migliori, Giovanni Battista; Centis, Rosella; Lange, Chris; Richardson, Morgan D Arcy; Sotgiu, Giovanni.
In: Current Opinion in Pulmonary Medicine, Vol. 16, No. 3, 05.2010, p. 171-179.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Emerging epidemic of drug-resistant tuberculosis in Europe, Russia, China, South America and Asia
T2 - Current status and global perspectives
AU - Migliori, Giovanni Battista
AU - Centis, Rosella
AU - Lange, Chris
AU - Richardson, Morgan D Arcy
AU - Sotgiu, Giovanni
PY - 2010/5
Y1 - 2010/5
N2 - Purpose of Review: Drug resistance, particularly through multidrug-resistant tuberculosis (TB) and extensively drug-resistant TB strains, poses a real threat to TB control worldwide. Recent reports from the WHO and the International Union Against Tuberculosis and Lung Disease demonstrate that the emerging epidemic of drug-resistant TB is a global problem, although emphasis has been placed on several 'hot spots' because of lack of good global data. Recent Findings: The present article is aimed at reviewing the available information on drug-resistant TB with special focus on the features of the epidemic in Europe, Russia, Latin America, Asia and specifically China, and to discuss the global perspectives related to drug-resistant TB control and care. Summary: Drug-resistant TB originates from different human errors, including misuse of anti-TB drugs and other reasons related to prescribers, patients and drug producers. Although there is an urgent need for new drugs, a sound public health approach is necessary for their introduction in clinical treatment settings to prevent/avoid creating additional resistance, as has already been observed for first and second-line anti-TB drugs in many settings.
AB - Purpose of Review: Drug resistance, particularly through multidrug-resistant tuberculosis (TB) and extensively drug-resistant TB strains, poses a real threat to TB control worldwide. Recent reports from the WHO and the International Union Against Tuberculosis and Lung Disease demonstrate that the emerging epidemic of drug-resistant TB is a global problem, although emphasis has been placed on several 'hot spots' because of lack of good global data. Recent Findings: The present article is aimed at reviewing the available information on drug-resistant TB with special focus on the features of the epidemic in Europe, Russia, Latin America, Asia and specifically China, and to discuss the global perspectives related to drug-resistant TB control and care. Summary: Drug-resistant TB originates from different human errors, including misuse of anti-TB drugs and other reasons related to prescribers, patients and drug producers. Although there is an urgent need for new drugs, a sound public health approach is necessary for their introduction in clinical treatment settings to prevent/avoid creating additional resistance, as has already been observed for first and second-line anti-TB drugs in many settings.
KW - Asia
KW - China
KW - Drug-resistant tuberculosis
KW - Europe
KW - Extensively drug-resistant tuberculosis
KW - Latin America
KW - Multidrug-resistant tuberculosis
KW - Russia
KW - Tuberculosis
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UR - http://www.scopus.com/inward/citedby.url?scp=77951048363&partnerID=8YFLogxK
U2 - 10.1097/MCP.0b013e328337573e
DO - 10.1097/MCP.0b013e328337573e
M3 - Article
C2 - 20134324
AN - SCOPUS:77951048363
VL - 16
SP - 171
EP - 179
JO - Current Opinion in Pulmonary Medicine
JF - Current Opinion in Pulmonary Medicine
SN - 1070-5287
IS - 3
ER -