Emerging epidemic of drug-resistant tuberculosis in Europe, Russia, China, South America and Asia: Current status and global perspectives

Giovanni Battista Migliori, Rosella Centis, Chris Lange, Morgan D Arcy Richardson, Giovanni Sotgiu

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose of Review: Drug resistance, particularly through multidrug-resistant tuberculosis (TB) and extensively drug-resistant TB strains, poses a real threat to TB control worldwide. Recent reports from the WHO and the International Union Against Tuberculosis and Lung Disease demonstrate that the emerging epidemic of drug-resistant TB is a global problem, although emphasis has been placed on several 'hot spots' because of lack of good global data. Recent Findings: The present article is aimed at reviewing the available information on drug-resistant TB with special focus on the features of the epidemic in Europe, Russia, Latin America, Asia and specifically China, and to discuss the global perspectives related to drug-resistant TB control and care. Summary: Drug-resistant TB originates from different human errors, including misuse of anti-TB drugs and other reasons related to prescribers, patients and drug producers. Although there is an urgent need for new drugs, a sound public health approach is necessary for their introduction in clinical treatment settings to prevent/avoid creating additional resistance, as has already been observed for first and second-line anti-TB drugs in many settings.

Original languageEnglish
Pages (from-to)171-179
Number of pages9
JournalCurrent Opinion in Pulmonary Medicine
Volume16
Issue number3
DOIs
Publication statusPublished - May 2010

Keywords

  • Asia
  • China
  • Drug-resistant tuberculosis
  • Europe
  • Extensively drug-resistant tuberculosis
  • Latin America
  • Multidrug-resistant tuberculosis
  • Russia
  • Tuberculosis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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