Emerging issues on comprehensive hemophilia care: Preventing, identifying, and monitoring age-related comorbidities

Antonio Coppola, Cristina Santoro, Massimo Franchini, Caterina Mannucci, Selene Mogavero, Angeloclaudio Molinari, Piercarla Schinco, Annarita Tagliaferri, Ritacarlotta Santoro

Research output: Contribution to journalArticlepeer-review

Abstract

Life expectancy for persons with hemophilia (PWH) has considerably increased in the last decades as a direct result of the availability of modern therapies to control the clotting defect. Because their life expectancy now matches that of the general population, PWH are experiencing age-related comorbidities, such as, cardiovascular diseases, metabolic syndrome, renal diseases, sexuality issues, malignancies, and neurologic problems, that until recently have been rarely seen in this group of patients. In this article, we present a summary of the current knowledge on the aging PWH along with the clinical approaches that may be integrated into the routine comprehensive care of these patients for preventing, diagnosing, and monitoring age-related comorbidities. In general, patients with and without hemophilia should receive similar care, with close collaboration between the physician treating PWH and the specialty expert treating the comorbid disease.

Original languageEnglish
Pages (from-to)794-802
Number of pages9
JournalSeminars in Thrombosis and Hemostasis
Volume39
Issue number7
DOIs
Publication statusPublished - 2013

Keywords

  • aging
  • check-up
  • comorbidities
  • comprehensive-care
  • hemophilia

ASJC Scopus subject areas

  • Hematology
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Emerging issues on comprehensive hemophilia care: Preventing, identifying, and monitoring age-related comorbidities'. Together they form a unique fingerprint.

Cite this