TY - JOUR
T1 - Emerging issues on comprehensive hemophilia care
T2 - Preventing, identifying, and monitoring age-related comorbidities
AU - Coppola, Antonio
AU - Santoro, Cristina
AU - Franchini, Massimo
AU - Mannucci, Caterina
AU - Mogavero, Selene
AU - Molinari, Angeloclaudio
AU - Schinco, Piercarla
AU - Tagliaferri, Annarita
AU - Santoro, Ritacarlotta
PY - 2013
Y1 - 2013
N2 - Life expectancy for persons with hemophilia (PWH) has considerably increased in the last decades as a direct result of the availability of modern therapies to control the clotting defect. Because their life expectancy now matches that of the general population, PWH are experiencing age-related comorbidities, such as, cardiovascular diseases, metabolic syndrome, renal diseases, sexuality issues, malignancies, and neurologic problems, that until recently have been rarely seen in this group of patients. In this article, we present a summary of the current knowledge on the aging PWH along with the clinical approaches that may be integrated into the routine comprehensive care of these patients for preventing, diagnosing, and monitoring age-related comorbidities. In general, patients with and without hemophilia should receive similar care, with close collaboration between the physician treating PWH and the specialty expert treating the comorbid disease.
AB - Life expectancy for persons with hemophilia (PWH) has considerably increased in the last decades as a direct result of the availability of modern therapies to control the clotting defect. Because their life expectancy now matches that of the general population, PWH are experiencing age-related comorbidities, such as, cardiovascular diseases, metabolic syndrome, renal diseases, sexuality issues, malignancies, and neurologic problems, that until recently have been rarely seen in this group of patients. In this article, we present a summary of the current knowledge on the aging PWH along with the clinical approaches that may be integrated into the routine comprehensive care of these patients for preventing, diagnosing, and monitoring age-related comorbidities. In general, patients with and without hemophilia should receive similar care, with close collaboration between the physician treating PWH and the specialty expert treating the comorbid disease.
KW - aging
KW - check-up
KW - comorbidities
KW - comprehensive-care
KW - hemophilia
UR - http://www.scopus.com/inward/record.url?scp=84885083804&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84885083804&partnerID=8YFLogxK
U2 - 10.1055/s-0033-1354424
DO - 10.1055/s-0033-1354424
M3 - Article
C2 - 24014070
AN - SCOPUS:84885083804
VL - 39
SP - 794
EP - 802
JO - Seminars in Thrombosis and Hemostasis
JF - Seminars in Thrombosis and Hemostasis
SN - 0094-6176
IS - 7
ER -