Abstract
Background: BRCA1 and BRCA2 mutations are associated with a higher risk of breast and ovarian tumors. This study evaluated the emotional states of women 1 month after having received the results of the genetic test and assessed eventual associations with the type of outcome, personal/familiar disease history and major socio-demographic variables. Methods: The study, an observational retrospective one, involved 91 women, evaluated 1 month after receiving their results. Patients were administered the Hospital Anxiety and Depression Scale, the Profile of Mood States and emotional Thermometers. Results: Anxiety was significantly higher than depression (p < 0.001), and 21.3% and 21.3% of the sample were, respectively, possible and probable cases for anxiety, whereas 13.5% and 10.1% were possible and probable cases for depression. Within the six mood states, Confusion-Bewilderment (M = 48.5) was the lowest, whereas Fatigue-Inertia (M = 52.3) was the highest. Differences were recorded within the ten assessed emotions too. Being a proband/nonproband and being or not a cancer patient were associated with many tested variables. Conclusion: The psycho-emotional screening of women undertaking genetic counseling is relevant and should cover a large range of dimensions.
| Original language | English |
|---|---|
| Article number | 16 |
| Number of pages | 7 |
| Journal | Hereditary Cancer in Clinical Practice |
| Volume | 15 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Oct 2 2017 |
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Keywords
- BRCA1/2
- Emotions
- Genetic counseling
- Mood states
- Psychological distress
ASJC Scopus subject areas
- Oncology
- Genetics(clinical)
Cite this
Emotional impact on the results of BRCA1 and BRCA2 genetic test : An observational retrospective study. / Mella, Sara; Muzzatti, Barbara; Dolcetti, Riccardo; Annunziata, Maria Antonietta.
In: Hereditary Cancer in Clinical Practice, Vol. 15, No. 1, 16, 02.10.2017.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Emotional impact on the results of BRCA1 and BRCA2 genetic test
T2 - An observational retrospective study
AU - Mella, Sara
AU - Muzzatti, Barbara
AU - Dolcetti, Riccardo
AU - Annunziata, Maria Antonietta
PY - 2017/10/2
Y1 - 2017/10/2
N2 - Background: BRCA1 and BRCA2 mutations are associated with a higher risk of breast and ovarian tumors. This study evaluated the emotional states of women 1 month after having received the results of the genetic test and assessed eventual associations with the type of outcome, personal/familiar disease history and major socio-demographic variables. Methods: The study, an observational retrospective one, involved 91 women, evaluated 1 month after receiving their results. Patients were administered the Hospital Anxiety and Depression Scale, the Profile of Mood States and emotional Thermometers. Results: Anxiety was significantly higher than depression (p < 0.001), and 21.3% and 21.3% of the sample were, respectively, possible and probable cases for anxiety, whereas 13.5% and 10.1% were possible and probable cases for depression. Within the six mood states, Confusion-Bewilderment (M = 48.5) was the lowest, whereas Fatigue-Inertia (M = 52.3) was the highest. Differences were recorded within the ten assessed emotions too. Being a proband/nonproband and being or not a cancer patient were associated with many tested variables. Conclusion: The psycho-emotional screening of women undertaking genetic counseling is relevant and should cover a large range of dimensions.
AB - Background: BRCA1 and BRCA2 mutations are associated with a higher risk of breast and ovarian tumors. This study evaluated the emotional states of women 1 month after having received the results of the genetic test and assessed eventual associations with the type of outcome, personal/familiar disease history and major socio-demographic variables. Methods: The study, an observational retrospective one, involved 91 women, evaluated 1 month after receiving their results. Patients were administered the Hospital Anxiety and Depression Scale, the Profile of Mood States and emotional Thermometers. Results: Anxiety was significantly higher than depression (p < 0.001), and 21.3% and 21.3% of the sample were, respectively, possible and probable cases for anxiety, whereas 13.5% and 10.1% were possible and probable cases for depression. Within the six mood states, Confusion-Bewilderment (M = 48.5) was the lowest, whereas Fatigue-Inertia (M = 52.3) was the highest. Differences were recorded within the ten assessed emotions too. Being a proband/nonproband and being or not a cancer patient were associated with many tested variables. Conclusion: The psycho-emotional screening of women undertaking genetic counseling is relevant and should cover a large range of dimensions.
KW - BRCA1/2
KW - Emotions
KW - Genetic counseling
KW - Mood states
KW - Psychological distress
UR - http://www.scopus.com/inward/record.url?scp=85030689801&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85030689801&partnerID=8YFLogxK
U2 - 10.1186/s13053-017-0077-6
DO - 10.1186/s13053-017-0077-6
M3 - Article
AN - SCOPUS:85030689801
VL - 15
JO - Hereditary Cancer in Clinical Practice
JF - Hereditary Cancer in Clinical Practice
SN - 1731-2302
IS - 1
M1 - 16
ER -