Emotional susceptibility trait modulates insula responses and functional connectivity in flavor processing

Sjoerd J H Ebisch, Annalisa Bello, Grazia F. Spitoni, Mauro G. Perrucci, Vittorio Gallese, Giorgia Committeri, Concetta Pastorelli, Luigi Pizzamiglio

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The present study aimed at investigating the relationship between Emotional Susceptibility (ES), an aspect of the personality trait Neuroticism, and individual differences in the neural responses in anterior insula to primary sensory stimuli colored by affective valence, i.e., distasting or pleasantly tasting oral stimuli. In addition, it was studied whether intrinsic functional connectivity patterns of brain regions characterized by such differential responses could be related to ES. To this purpose 25 female participants underwent functional magnetic resonance imaging scanning, while being involved in a flavor experiment. During the experiment, flavor stimuli were administered consisting of small amounts of liquid with a different affective valence: neutral, pleasant, unpleasant. The results showed that individual differences in ES trait predicted distinct neural activity patterns to the different stimulus conditions in a region of left anterior insula that a previous meta-analysis revealed to be linked with olfacto-gustatory processing. Specifically, low ES was associated with enhanced neural responses to both pleasant and unpleasant stimuli, compared to neutral stimuli. By contrast, high ES participants showed equally strong neural responses to all types of stimuli without differentiating between the neutral and affective stimuli. Finally, during a task-free state, high ES trait appeared also to be related to decreased intrinsic functional connectivity between left anterior insula and left cerebellum. Our findings show that individual differences in ES are associated with differential anterior insula responses to primary sensory (flavor) stimuli as well as to intrinsic functional cortico-cerebellar connectivity, the latter suggesting a basis in the brain intrinsic functional architecture of the regulation of emotional experiences.

Original languageEnglish
Article number297
JournalFrontiers in Behavioral Neuroscience
Volume9
Issue numberNOVEMBER
DOIs
Publication statusPublished - Nov 5 2015

Fingerprint

Individuality
Brain
Cerebellum
Personality
Meta-Analysis
Magnetic Resonance Imaging
Neuroticism

Keywords

  • Cerebellum
  • Emotion
  • Emotional susceptibility
  • Gustation
  • Individual differences
  • Insula
  • Personality traits
  • Taste

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Cognitive Neuroscience
  • Neuropsychology and Physiological Psychology

Cite this

Ebisch, S. J. H., Bello, A., Spitoni, G. F., Perrucci, M. G., Gallese, V., Committeri, G., ... Pizzamiglio, L. (2015). Emotional susceptibility trait modulates insula responses and functional connectivity in flavor processing. Frontiers in Behavioral Neuroscience, 9(NOVEMBER), [297]. https://doi.org/10.3389/fnbeh.2015.00297

Emotional susceptibility trait modulates insula responses and functional connectivity in flavor processing. / Ebisch, Sjoerd J H; Bello, Annalisa; Spitoni, Grazia F.; Perrucci, Mauro G.; Gallese, Vittorio; Committeri, Giorgia; Pastorelli, Concetta; Pizzamiglio, Luigi.

In: Frontiers in Behavioral Neuroscience, Vol. 9, No. NOVEMBER, 297, 05.11.2015.

Research output: Contribution to journalArticle

Ebisch, SJH, Bello, A, Spitoni, GF, Perrucci, MG, Gallese, V, Committeri, G, Pastorelli, C & Pizzamiglio, L 2015, 'Emotional susceptibility trait modulates insula responses and functional connectivity in flavor processing', Frontiers in Behavioral Neuroscience, vol. 9, no. NOVEMBER, 297. https://doi.org/10.3389/fnbeh.2015.00297
Ebisch, Sjoerd J H ; Bello, Annalisa ; Spitoni, Grazia F. ; Perrucci, Mauro G. ; Gallese, Vittorio ; Committeri, Giorgia ; Pastorelli, Concetta ; Pizzamiglio, Luigi. / Emotional susceptibility trait modulates insula responses and functional connectivity in flavor processing. In: Frontiers in Behavioral Neuroscience. 2015 ; Vol. 9, No. NOVEMBER.
@article{1b27f433c6b34c028b11cbe13f830467,
title = "Emotional susceptibility trait modulates insula responses and functional connectivity in flavor processing",
abstract = "The present study aimed at investigating the relationship between Emotional Susceptibility (ES), an aspect of the personality trait Neuroticism, and individual differences in the neural responses in anterior insula to primary sensory stimuli colored by affective valence, i.e., distasting or pleasantly tasting oral stimuli. In addition, it was studied whether intrinsic functional connectivity patterns of brain regions characterized by such differential responses could be related to ES. To this purpose 25 female participants underwent functional magnetic resonance imaging scanning, while being involved in a flavor experiment. During the experiment, flavor stimuli were administered consisting of small amounts of liquid with a different affective valence: neutral, pleasant, unpleasant. The results showed that individual differences in ES trait predicted distinct neural activity patterns to the different stimulus conditions in a region of left anterior insula that a previous meta-analysis revealed to be linked with olfacto-gustatory processing. Specifically, low ES was associated with enhanced neural responses to both pleasant and unpleasant stimuli, compared to neutral stimuli. By contrast, high ES participants showed equally strong neural responses to all types of stimuli without differentiating between the neutral and affective stimuli. Finally, during a task-free state, high ES trait appeared also to be related to decreased intrinsic functional connectivity between left anterior insula and left cerebellum. Our findings show that individual differences in ES are associated with differential anterior insula responses to primary sensory (flavor) stimuli as well as to intrinsic functional cortico-cerebellar connectivity, the latter suggesting a basis in the brain intrinsic functional architecture of the regulation of emotional experiences.",
keywords = "Cerebellum, Emotion, Emotional susceptibility, Gustation, Individual differences, Insula, Personality traits, Taste",
author = "Ebisch, {Sjoerd J H} and Annalisa Bello and Spitoni, {Grazia F.} and Perrucci, {Mauro G.} and Vittorio Gallese and Giorgia Committeri and Concetta Pastorelli and Luigi Pizzamiglio",
year = "2015",
month = "11",
day = "5",
doi = "10.3389/fnbeh.2015.00297",
language = "English",
volume = "9",
journal = "Frontiers in Behavioral Neuroscience",
issn = "1662-5153",
publisher = "Frontiers Research Foundation",
number = "NOVEMBER",

}

TY - JOUR

T1 - Emotional susceptibility trait modulates insula responses and functional connectivity in flavor processing

AU - Ebisch, Sjoerd J H

AU - Bello, Annalisa

AU - Spitoni, Grazia F.

AU - Perrucci, Mauro G.

AU - Gallese, Vittorio

AU - Committeri, Giorgia

AU - Pastorelli, Concetta

AU - Pizzamiglio, Luigi

PY - 2015/11/5

Y1 - 2015/11/5

N2 - The present study aimed at investigating the relationship between Emotional Susceptibility (ES), an aspect of the personality trait Neuroticism, and individual differences in the neural responses in anterior insula to primary sensory stimuli colored by affective valence, i.e., distasting or pleasantly tasting oral stimuli. In addition, it was studied whether intrinsic functional connectivity patterns of brain regions characterized by such differential responses could be related to ES. To this purpose 25 female participants underwent functional magnetic resonance imaging scanning, while being involved in a flavor experiment. During the experiment, flavor stimuli were administered consisting of small amounts of liquid with a different affective valence: neutral, pleasant, unpleasant. The results showed that individual differences in ES trait predicted distinct neural activity patterns to the different stimulus conditions in a region of left anterior insula that a previous meta-analysis revealed to be linked with olfacto-gustatory processing. Specifically, low ES was associated with enhanced neural responses to both pleasant and unpleasant stimuli, compared to neutral stimuli. By contrast, high ES participants showed equally strong neural responses to all types of stimuli without differentiating between the neutral and affective stimuli. Finally, during a task-free state, high ES trait appeared also to be related to decreased intrinsic functional connectivity between left anterior insula and left cerebellum. Our findings show that individual differences in ES are associated with differential anterior insula responses to primary sensory (flavor) stimuli as well as to intrinsic functional cortico-cerebellar connectivity, the latter suggesting a basis in the brain intrinsic functional architecture of the regulation of emotional experiences.

AB - The present study aimed at investigating the relationship between Emotional Susceptibility (ES), an aspect of the personality trait Neuroticism, and individual differences in the neural responses in anterior insula to primary sensory stimuli colored by affective valence, i.e., distasting or pleasantly tasting oral stimuli. In addition, it was studied whether intrinsic functional connectivity patterns of brain regions characterized by such differential responses could be related to ES. To this purpose 25 female participants underwent functional magnetic resonance imaging scanning, while being involved in a flavor experiment. During the experiment, flavor stimuli were administered consisting of small amounts of liquid with a different affective valence: neutral, pleasant, unpleasant. The results showed that individual differences in ES trait predicted distinct neural activity patterns to the different stimulus conditions in a region of left anterior insula that a previous meta-analysis revealed to be linked with olfacto-gustatory processing. Specifically, low ES was associated with enhanced neural responses to both pleasant and unpleasant stimuli, compared to neutral stimuli. By contrast, high ES participants showed equally strong neural responses to all types of stimuli without differentiating between the neutral and affective stimuli. Finally, during a task-free state, high ES trait appeared also to be related to decreased intrinsic functional connectivity between left anterior insula and left cerebellum. Our findings show that individual differences in ES are associated with differential anterior insula responses to primary sensory (flavor) stimuli as well as to intrinsic functional cortico-cerebellar connectivity, the latter suggesting a basis in the brain intrinsic functional architecture of the regulation of emotional experiences.

KW - Cerebellum

KW - Emotion

KW - Emotional susceptibility

KW - Gustation

KW - Individual differences

KW - Insula

KW - Personality traits

KW - Taste

UR - http://www.scopus.com/inward/record.url?scp=84947759388&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84947759388&partnerID=8YFLogxK

U2 - 10.3389/fnbeh.2015.00297

DO - 10.3389/fnbeh.2015.00297

M3 - Article

AN - SCOPUS:84947759388

VL - 9

JO - Frontiers in Behavioral Neuroscience

JF - Frontiers in Behavioral Neuroscience

SN - 1662-5153

IS - NOVEMBER

M1 - 297

ER -