Encapsulated well-differentiated follicular-patterned thyroid carcinomas do not play a significant role in the fatality rates from thyroid carcinoma

Simonetta Piana, Andrea Frasoldati, Enza Di Felice, Giorgio Gardini, Giovanni Tallini, Juan Rosai

Research output: Contribution to journalArticlepeer-review

Abstract

A cohort of 1039 consecutive cases of thyroid carcinoma treated at a single institution and followed for an average of 11.9 years or until death included 102 encapsulated well-differentiated follicular-patterned tumors that had been diagnosed as carcinoma because of complete capsular invasion and/or papillary carcinoma-type nuclei. None of these cases were among the 67 patients from the cohort who died as a result of their thyroid carcinoma. The results of this study and a critical review of the pertinent literature indicate that tumors with these features are associated with an extremely favorable outcome and that they do not play a significant role in the fatality rate of thyroid carcinoma.

Original languageEnglish
Pages (from-to)868-872
Number of pages5
JournalAmerican Journal of Surgical Pathology
Volume34
Issue number6
DOIs
Publication statusPublished - Jun 2010

Keywords

  • Minimally invasive follicular carcinoma
  • Thyroid cancer fatality rates
  • Thyroid carcinoma

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine
  • Surgery

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