End-Stage Renal Disease After Renal Surgery in Patients with Normal Preoperative Kidney Function: Balancing Surgical Strategy and Individual Disorders at Baseline

Umberto Capitanio, Alessandro Larcher, Carlo Terrone, Alessandro Antonelli, Alessandro Volpe, Cristian Fiori, Maria Furlan, Federico Dehò, Andrea Minervini, Sergio Serni, Francesco Porpiglia, Francesco Trevisani, Andrea Salonia, Marco Carini, Claudio Simeone, Francesco Montorsi, Roberto Bertini

Research output: Contribution to journalArticle

Abstract

Although nephron-sparing surgery (NSS) has demonstrated benefit in terms of renal function preservation, it is unclear whether NSS might also decrease the risk of end-stage renal disease (ESRD) relative to radical nephrectomy (RN). In the current paper, we aimed to report the rate and the predictors of ESRD after surgery, accounting for detailed individual baseline characteristics and comorbidities. A multi-institutional collaboration among five European tertiary care centers allowed study of 2027 patients with normal preoperative renal function and a clinically localized T1abN0M0 renal mass. Cox regression analyses were used to predict the risk of ESRD (defined as the onset of a postoperative estimated glomerular filtration rate
Original languageEnglish
Pages (from-to)558 - 561
Number of pages4
JournalEuropean Urology
Volume70
Issue number4
DOIs
Publication statusPublished - Oct 1 2016

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Keywords

  • Dialysis
  • End-stage renal disease
  • Kidney cancer
  • Nephron-sparing surgery
  • Partial nephrectomy
  • Radical nephrectomy

ASJC Scopus subject areas

  • Urology

Cite this

Capitanio, U., Larcher, A., Terrone, C., Antonelli, A., Volpe, A., Fiori, C., Furlan, M., Dehò, F., Minervini, A., Serni, S., Porpiglia, F., Trevisani, F., Salonia, A., Carini, M., Simeone, C., Montorsi, F., & Bertini, R. (2016). End-Stage Renal Disease After Renal Surgery in Patients with Normal Preoperative Kidney Function: Balancing Surgical Strategy and Individual Disorders at Baseline. European Urology, 70(4), 558 - 561. https://doi.org/10.1016/j.eururo.2016.03.023