Endocannabinoids and reproductive events in health and disease

Natalia Battista, Monica Bari, Mauro Maccarrone

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The lasting research on the endocannabinoid system (ECS) has now provided solid and convincing evidence that proves the detrimental effects of recreational drug abuse (a growing habit among teenagers) on fertility. Endocannabinoids (eCBs) affect reproductive events from gametogenesis to fertilization, from embryo implantation to the final outcome of pregnancy and, thus, they have been proposed as suitable biomarkers to predict the reproductive potential of male and female gametes in clinical practice. Novel tools for reproductive medicine are highly sought after, and here we report the latest findings on the impact of the ECS on fertility, demonstrating how basic research can be translated into new medical strategies.

Original languageEnglish
Title of host publicationEndocannabinoids
PublisherSpringer International Publishing
Pages341-365
Number of pages25
ISBN (Print)9783319208251, 9783319208244
DOIs
Publication statusPublished - Sep 25 2015

Keywords

  • AEA Anandamide
  • Biomarkers
  • Endocannabinoid system
  • Infertility
  • Reproduction

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Neuroscience(all)
  • Immunology and Microbiology(all)

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