Endocarditis in patients with bioprostheses: pathology and clinical correlations

Claudio Zussa, Marco R. Galloni, Giuseppe F. Zattera, Stefano Pansini, Michele di Summa, Giuseppe A. Poletti, Gianmaria Ottino, Mario Morea

Research output: Contribution to journalArticlepeer-review


We studied 13 porcine bioprostheses removed from patients with endocarditis at our institute during the last 4.5 years. All bioprostheses had been removed at reoperation and were analyzed using anatomical and histological techniques. Each bioprosthesis was found to have developed rather constant lesions which were not related to the type of bioprosthesis. The stage of infection was not related to the duration of implantation. The presence of perivalvular abscesses was an ominous finding, often being the seat of persistent endocarditis. Our good clinical results of reoperation lead us to suggest that this be performed early once valvular or prosthetic malfunction is detected. Bioprostheses are, in our experience, the best choice in the surgical treatement of prosthetic valve endocarditis.

Original languageEnglish
Pages (from-to)719-732
Number of pages14
JournalInternational Journal of Cardiology
Issue number6
Publication statusPublished - 1984


  • electron microscopy
  • histology
  • valve replacement

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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