Endocervical detection of CIN. Cytobrush versus cotton

F. Schettino, M. Sideri, L. Cangini, M. Candiani, E. Zannoni, R. Maggi, A. Ferrari

Research output: Contribution to journalArticlepeer-review


Correct methods of sampling are essential for obtaining adequate smears for cytological diagnosis of cervicovaginal abnormalities. In this paper we report on 3 methods of sampling, Ayre spatula, cotton swab and cytobrush on 89 patients who underwent repeat smear and colposcopic examinations because of abnormal screening smears. The cytobrush device was better than Ayre spatula or cotton in collecting both endocervical and neoplastic cells. However, the combination of spatula and cotton was almost the same as spatula and cytobrush in recovering neoplastic cells. Therefore the rate of cervical intraepithelial neoplasia (CIN) diagnosis is more influenced by an adequate sampling of the endocervix than by the type of endocervical device.

Original languageEnglish
Pages (from-to)234-236
Number of pages3
JournalEuropean Journal of Gynaecological Oncology
Issue number3
Publication statusPublished - 1993


  • cervix dysplasia
  • cytodiagnosis
  • cytological technics

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology


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