Endocrine aspects of coeliac disease

Lorenzo Iughetti, Sabrina Bulgarelli, Silvia Forese, Renata Lorini, Fiorella Balli, Sergio Bernasconi

Research output: Contribution to journalArticlepeer-review


Coeliac disease (CD) is a permanent intolerance to gluten that results in damage of the small intestinal mucosa, and it is one of the common causes of chronic malabsorption in children. It is well known that patients with CD are at great risk of malignant complications, but in patients with CD many other disorders have been recognized. Autoimmunity diseases, such as type 1 diabetes mellitus, thyroid diseases, and autoimmune polyglandular syndromes are known to be associated with CD, and they seem to be related to gluten exposure. Growth, bone metabolism, and fertility can be affected in patients with CD, especially if they are not on a glutenfree diet. We review the literature on endocrine aspects of CD, because patients with CD are at great risk of developing endocrine disorders.

Original languageEnglish
Pages (from-to)805-818
Number of pages14
JournalJournal of Pediatric Endocrinology and Metabolism
Issue number6
Publication statusPublished - 2003


  • Autoimmune polyglandular syndromes
  • Bone metabolism
  • Coeliac disease
  • Diabetes mellitus
  • Fertility
  • Growth
  • Thyroid disorders

ASJC Scopus subject areas

  • Endocrinology
  • Pediatrics, Perinatology, and Child Health


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