Endocrine aspects of women's sexual function

Margaret E. Wierman, Rossella E. Nappi, Nancy Avis, Susan R. Davis, Ferdinand Labrie, Willam Rosner, Jan L. Shifren

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

Introduction: Endocrine changes during aging as well as endocrine disorders may either directly or indirectly modulate female sexual function by altering sex hormones, or by impacting on vascular, neurogenic, or psychologic factors. Aim: To review information on the impact of the hormonal changes associated with aging or those caused by endocrine disorders on female sexual function and current information on the risks and benefits of hormonal treatments. Methods: Committee members outlined topics and reviewed the published literature on endocrine aspects of female sexual function over a 2-year period. Presentation of the recommendations were presented at the International Consultation on Sexual Medicine Paris, France 2009 and revised accordingly. Main Outcome Measures: Quality of data published in the literature and recommendations were based on the GRADES system. Results: Recommendations and guidelines concerning the role of sex hormones and endocrine disorders in female sexual function were derived. Conclusions: Hormones are only one component of the many factors that contribute to normal sexual function in women. Further research is needed as to the impact of hormones and endocrine disorders on female sexual dysfunction and the benefits and risks of hormonal therapies.

Original languageEnglish
Pages (from-to)561-585
Number of pages25
JournalJournal of Sexual Medicine
Volume7
Issue number1 PART 2
DOIs
Publication statusPublished - Jan 2010

Fingerprint

Gonadal Steroid Hormones
Hormones
Committee Membership
Paris
France
Blood Vessels
Referral and Consultation
Medicine
Outcome Assessment (Health Care)
Guidelines
Therapeutics
Research
Data Accuracy

Keywords

  • Diabetes
  • Estrogen
  • Hypoactive sexual desire disorder (HSDD)
  • Menopause
  • Metabolic syndrome
  • Polycystic ovarian syndrome (PCOS)
  • Premature ovarian failure (POF)
  • Testosterone

ASJC Scopus subject areas

  • Urology
  • Obstetrics and Gynaecology
  • Reproductive Medicine

Cite this

Wierman, M. E., Nappi, R. E., Avis, N., Davis, S. R., Labrie, F., Rosner, W., & Shifren, J. L. (2010). Endocrine aspects of women's sexual function. Journal of Sexual Medicine, 7(1 PART 2), 561-585. https://doi.org/10.1111/j.1743-6109.2009.01629.x

Endocrine aspects of women's sexual function. / Wierman, Margaret E.; Nappi, Rossella E.; Avis, Nancy; Davis, Susan R.; Labrie, Ferdinand; Rosner, Willam; Shifren, Jan L.

In: Journal of Sexual Medicine, Vol. 7, No. 1 PART 2, 01.2010, p. 561-585.

Research output: Contribution to journalArticle

Wierman, ME, Nappi, RE, Avis, N, Davis, SR, Labrie, F, Rosner, W & Shifren, JL 2010, 'Endocrine aspects of women's sexual function', Journal of Sexual Medicine, vol. 7, no. 1 PART 2, pp. 561-585. https://doi.org/10.1111/j.1743-6109.2009.01629.x
Wierman ME, Nappi RE, Avis N, Davis SR, Labrie F, Rosner W et al. Endocrine aspects of women's sexual function. Journal of Sexual Medicine. 2010 Jan;7(1 PART 2):561-585. https://doi.org/10.1111/j.1743-6109.2009.01629.x
Wierman, Margaret E. ; Nappi, Rossella E. ; Avis, Nancy ; Davis, Susan R. ; Labrie, Ferdinand ; Rosner, Willam ; Shifren, Jan L. / Endocrine aspects of women's sexual function. In: Journal of Sexual Medicine. 2010 ; Vol. 7, No. 1 PART 2. pp. 561-585.
@article{565ca570f7b9406fb56a1c8308cfa4f0,
title = "Endocrine aspects of women's sexual function",
abstract = "Introduction: Endocrine changes during aging as well as endocrine disorders may either directly or indirectly modulate female sexual function by altering sex hormones, or by impacting on vascular, neurogenic, or psychologic factors. Aim: To review information on the impact of the hormonal changes associated with aging or those caused by endocrine disorders on female sexual function and current information on the risks and benefits of hormonal treatments. Methods: Committee members outlined topics and reviewed the published literature on endocrine aspects of female sexual function over a 2-year period. Presentation of the recommendations were presented at the International Consultation on Sexual Medicine Paris, France 2009 and revised accordingly. Main Outcome Measures: Quality of data published in the literature and recommendations were based on the GRADES system. Results: Recommendations and guidelines concerning the role of sex hormones and endocrine disorders in female sexual function were derived. Conclusions: Hormones are only one component of the many factors that contribute to normal sexual function in women. Further research is needed as to the impact of hormones and endocrine disorders on female sexual dysfunction and the benefits and risks of hormonal therapies.",
keywords = "Diabetes, Estrogen, Hypoactive sexual desire disorder (HSDD), Menopause, Metabolic syndrome, Polycystic ovarian syndrome (PCOS), Premature ovarian failure (POF), Testosterone",
author = "Wierman, {Margaret E.} and Nappi, {Rossella E.} and Nancy Avis and Davis, {Susan R.} and Ferdinand Labrie and Willam Rosner and Shifren, {Jan L.}",
year = "2010",
month = "1",
doi = "10.1111/j.1743-6109.2009.01629.x",
language = "English",
volume = "7",
pages = "561--585",
journal = "Journal of Sexual Medicine",
issn = "1743-6095",
publisher = "Wiley-Blackwell",
number = "1 PART 2",

}

TY - JOUR

T1 - Endocrine aspects of women's sexual function

AU - Wierman, Margaret E.

AU - Nappi, Rossella E.

AU - Avis, Nancy

AU - Davis, Susan R.

AU - Labrie, Ferdinand

AU - Rosner, Willam

AU - Shifren, Jan L.

PY - 2010/1

Y1 - 2010/1

N2 - Introduction: Endocrine changes during aging as well as endocrine disorders may either directly or indirectly modulate female sexual function by altering sex hormones, or by impacting on vascular, neurogenic, or psychologic factors. Aim: To review information on the impact of the hormonal changes associated with aging or those caused by endocrine disorders on female sexual function and current information on the risks and benefits of hormonal treatments. Methods: Committee members outlined topics and reviewed the published literature on endocrine aspects of female sexual function over a 2-year period. Presentation of the recommendations were presented at the International Consultation on Sexual Medicine Paris, France 2009 and revised accordingly. Main Outcome Measures: Quality of data published in the literature and recommendations were based on the GRADES system. Results: Recommendations and guidelines concerning the role of sex hormones and endocrine disorders in female sexual function were derived. Conclusions: Hormones are only one component of the many factors that contribute to normal sexual function in women. Further research is needed as to the impact of hormones and endocrine disorders on female sexual dysfunction and the benefits and risks of hormonal therapies.

AB - Introduction: Endocrine changes during aging as well as endocrine disorders may either directly or indirectly modulate female sexual function by altering sex hormones, or by impacting on vascular, neurogenic, or psychologic factors. Aim: To review information on the impact of the hormonal changes associated with aging or those caused by endocrine disorders on female sexual function and current information on the risks and benefits of hormonal treatments. Methods: Committee members outlined topics and reviewed the published literature on endocrine aspects of female sexual function over a 2-year period. Presentation of the recommendations were presented at the International Consultation on Sexual Medicine Paris, France 2009 and revised accordingly. Main Outcome Measures: Quality of data published in the literature and recommendations were based on the GRADES system. Results: Recommendations and guidelines concerning the role of sex hormones and endocrine disorders in female sexual function were derived. Conclusions: Hormones are only one component of the many factors that contribute to normal sexual function in women. Further research is needed as to the impact of hormones and endocrine disorders on female sexual dysfunction and the benefits and risks of hormonal therapies.

KW - Diabetes

KW - Estrogen

KW - Hypoactive sexual desire disorder (HSDD)

KW - Menopause

KW - Metabolic syndrome

KW - Polycystic ovarian syndrome (PCOS)

KW - Premature ovarian failure (POF)

KW - Testosterone

UR - http://www.scopus.com/inward/record.url?scp=74049129793&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=74049129793&partnerID=8YFLogxK

U2 - 10.1111/j.1743-6109.2009.01629.x

DO - 10.1111/j.1743-6109.2009.01629.x

M3 - Article

C2 - 20092453

AN - SCOPUS:74049129793

VL - 7

SP - 561

EP - 585

JO - Journal of Sexual Medicine

JF - Journal of Sexual Medicine

SN - 1743-6095

IS - 1 PART 2

ER -