Abstract
Gastric endocrine tumors are classified as well differentiated and poorly differentiated. The large majority of well differentiated endocrine tumors are argyrophil enterochromaffin-like (ECL) cell tumors and can be subdivided in Type 1, associated with chronic atrophic gastritis, Type 2 associated with multiple endocrine neoplasia 1 and Zollinger-Ellison syndrome (MEN1-ZES) and Type 3, sporadic, or not associated to specific gastric pathology. Type 1 and 2 tumors are mostly benign in behaviour, while Type 3 tumors are low grade malignant carcinomas. The poorly differentiated endocrine tumors of the stomach are highly malignant and aggressive carcinomas.
Original language | English |
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Pages (from-to) | 19-22 |
Number of pages | 4 |
Journal | Medecine Biologie Environment |
Volume | 25 |
Issue number | 1 |
Publication status | Published - 1997 |
Keywords
- Argyrophilia
- Dysplasia
- ECL cells
- Electron microscopy
- Endocrine cells
- Immunohistochemistry
- Neoplasia
- Stomach
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)