Endocytic control of signaling at the plasma membrane

Elisa Barbieri, Pier Paolo Di Fiore, Sara Sigismund

Research output: Contribution to journalArticlepeer-review


Signaling is regulated by endocytosis at multiple levels along endocytic routes. Endocytic control of signaling starts already at the plasma membrane, where cells employ different mechanisms to finely tune the type and strength of signals emanating from the cell surface. Here, we will review some of the most recently described endocytic mechanisms controlling signaling at the plasma membrane, through the regulation of internalization dynamics and through the integration of different internalization pathways triggered by canonical chemical stimuli or physical forces.

Original languageEnglish
Pages (from-to)21-27
Number of pages7
JournalCurrent Opinion in Cell Biology
Publication statusPublished - Apr 1 2016

ASJC Scopus subject areas

  • Cell Biology


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