TY - JOUR
T1 - Endocytic control of signaling at the plasma membrane
AU - Barbieri, Elisa
AU - Di Fiore, Pier Paolo
AU - Sigismund, Sara
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Signaling is regulated by endocytosis at multiple levels along endocytic routes. Endocytic control of signaling starts already at the plasma membrane, where cells employ different mechanisms to finely tune the type and strength of signals emanating from the cell surface. Here, we will review some of the most recently described endocytic mechanisms controlling signaling at the plasma membrane, through the regulation of internalization dynamics and through the integration of different internalization pathways triggered by canonical chemical stimuli or physical forces.
AB - Signaling is regulated by endocytosis at multiple levels along endocytic routes. Endocytic control of signaling starts already at the plasma membrane, where cells employ different mechanisms to finely tune the type and strength of signals emanating from the cell surface. Here, we will review some of the most recently described endocytic mechanisms controlling signaling at the plasma membrane, through the regulation of internalization dynamics and through the integration of different internalization pathways triggered by canonical chemical stimuli or physical forces.
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U2 - 10.1016/j.ceb.2016.01.012
DO - 10.1016/j.ceb.2016.01.012
M3 - Article
AN - SCOPUS:84957575374
VL - 39
SP - 21
EP - 27
JO - Current Opinion in Cell Biology
JF - Current Opinion in Cell Biology
SN - 0955-0674
ER -