TY - JOUR
T1 - Endometriosis-associated clear cell carcinoma of the abdominal wall after caesarean section
T2 - A case report and review of the literature
AU - Giannella, Luca
AU - Serri, Matteo
AU - Maccaroni, Elena
AU - Di Giuseppe, Jacopo
AU - Carpini, Giovanni Delli
AU - Berardi, Rossana
AU - Sopracordevole, Francesco
AU - Ciavattini, Andrea
N1 - Publisher Copyright:
© 2020 International Institute of Anticancer Research. All rights reserved.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/8
Y1 - 2020/8
N2 - Background/Aim: Clear cell carcinoma of the abdominal wall is a sporadic event. To date, about thirty cases have been reported in the literature. This article provides a case report and literature review of an infrequent occurrence with poor prognosis. Case Report: A 45-year-old woman with pelvic pain and an abdominal mass came to our attention. Her medical history was notable for two previous cesarean sections. Physical examination revealed a smooth, multilocular mass measuring about 20 cm, arising from the previous surgical scar. Histology revealed clear-cell carcinoma resulting from the transformation of abdominal wall endometriosis. Given the disease extent, the patient underwent front-line chemotherapy. After several and multiple chemotherapy regimens, there was a disease progression that resulted in the death of the patient in 7 months. The literature review showed that a previous cesarean section was present in 91% of cases. Besides, approximately 26.5% of women died within 12 months of being diagnosed. The mean age of women was 45.88 years, while the average size of the lesion was 11 cm. Conclusion: Clear cell carcinoma is a rare but occurring event. Middleaged women showing an abdominal wall mass in close relation with a surgical scar from a previous cesarean section must be promptly investigated. Treatment options usually include surgery and chemotherapy with poor results.
AB - Background/Aim: Clear cell carcinoma of the abdominal wall is a sporadic event. To date, about thirty cases have been reported in the literature. This article provides a case report and literature review of an infrequent occurrence with poor prognosis. Case Report: A 45-year-old woman with pelvic pain and an abdominal mass came to our attention. Her medical history was notable for two previous cesarean sections. Physical examination revealed a smooth, multilocular mass measuring about 20 cm, arising from the previous surgical scar. Histology revealed clear-cell carcinoma resulting from the transformation of abdominal wall endometriosis. Given the disease extent, the patient underwent front-line chemotherapy. After several and multiple chemotherapy regimens, there was a disease progression that resulted in the death of the patient in 7 months. The literature review showed that a previous cesarean section was present in 91% of cases. Besides, approximately 26.5% of women died within 12 months of being diagnosed. The mean age of women was 45.88 years, while the average size of the lesion was 11 cm. Conclusion: Clear cell carcinoma is a rare but occurring event. Middleaged women showing an abdominal wall mass in close relation with a surgical scar from a previous cesarean section must be promptly investigated. Treatment options usually include surgery and chemotherapy with poor results.
KW - Abdominal wall endometriosis
KW - Cesarean scar endometriosis
KW - Chemotherapy
KW - Clear cell carcinoma
KW - Endometriosis
KW - Surgery
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U2 - 10.21873/invivo.12021
DO - 10.21873/invivo.12021
M3 - Article
VL - 34
SP - 2147
EP - 2152
JO - In Vivo
JF - In Vivo
SN - 0258-851X
IS - 4
ER -