Endomyocardial biopsy guided by intracardiac echocardiography as a key step in intracardiac mass diagnosis

Marco Zanobini, Antonio Dello Russo, Matteo Saccocci, Sergio Conti, Elisa De Camilli, Giulia Vettor, Valentina Catto, Maurizio Roberto, Cesare Fiorentini, Giuseppe Viale, Claudio Tondo, Michela Casella

Research output: Contribution to journalArticlepeer-review


BACKGROUND: Based on a plenty of different applications, intracardiac echocardiography (ICE) is now a well-established technology in complex electrophysiological procedures. Recently, ICE has become the most widely used ultrasound-based imaging tool to guide diagnostic endomyocardial biopsy (EMB). EMB of cardiac mass guided by ICE is an interesting application of ICE. Allowing a correct positioning of the bioptome, ICE reduce the procedure-related risks and the need of a diagnostic open-chest procedure reserving the more invasive approach to selected cases.

CASE PRESENTATION: Hereby we report a case series of right ventricular masses in which the EMB was safely and effectively performed under ICE guidance giving essential information for planning the therapeutic strategy.

CONCLUSIONS: The diagnosis of both metastatic and primary cardiac tumors relies on the histopathological analyses. The endomyocardial biopsy is a valuable tool for preoperative diagnosis and surgical planning of intracardiac masses suspected for tumors. In our experience, the use of ICE for right ventricle EMB of an intracardiac mass is an attractive modality thanks to the precise localization of the cardiac structures and the ability to guide bioptic withdrawal in the target area.

Original languageEnglish
Pages (from-to)15
JournalBMC Cardiovascular Disorders
Issue number1
Publication statusPublished - Jan 30 2018


  • Aged
  • Echocardiography
  • Female
  • Heart Neoplasms/diagnostic imaging
  • Humans
  • Image-Guided Biopsy/methods
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Myocardium/pathology
  • Predictive Value of Tests
  • Prognosis


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