Endoscopic mucosal resection and endoscopic submucosal dissection for colorectal lesions: A systematic review

Antonella De Ceglie, Cesare Hassan, Benedetto Mangiavillano, Takahisa Matsuda, Yutaka Saito, Lorenzo Ridola, Pradeep Bhandari, Federica Boeri, Massimo Conio

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To assess the efficacy and safety of endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) for the treatment of colorectal lesions. Methods: A literature search was conducted from January 2000 to May 2015. The main outcomes were: recurrence after ". en bloc" and ". piecemeal" resection; procedure related adverse events; the EMR endoscopic success rate and the completely eradicated resection rate (R0) after ESD. Results: A total of 66 studies were included in the analysis. The total number of lesions was 17950 (EMR: 11.873; ESD: 6077). Recurrence rate was higher in the EMR than ESD group (765/7303l vs. 50/3910 OR 8.19, 95% CI 6.2-10.9 p.

Original languageEnglish
JournalCritical Reviews in Oncology/Hematology
DOIs
Publication statusAccepted/In press - Jan 12 2016

Keywords

  • Colorectal lesion
  • EMR
  • Endoscopic mucosa resection
  • Endoscopic submucosal dissection
  • ESD
  • Laterally spreading tumor
  • LST

ASJC Scopus subject areas

  • Oncology
  • Hematology
  • Geriatrics and Gerontology

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