Endoscopic mucosal resection of large hyperplastic polyps in 3 patients with Barrett's esophagus

Antonella De Ceglie, Gabriella Lapertosa, Sabrina Blanchi, Marcello Di Muzio, Massimo Picasso, Rosangela Filiberti, Francesco Scotto, Massimo Conio

Research output: Contribution to journalArticle

Abstract

Aim: To report the endoscopic treatment of large hyperplastic polyps of the esophagus and esophagogastric junction (EGJ) associated with Barrett's esophagus (BE) with low-grade dysplasia (LGD), by endoscopic mucosal resection (EMR). Methods: Cap fitted EMR (EMR-C) was performed in 3 patients with hyperplastic-inflammatory polyps (HIPs) and BE. Results: The polyps were successfully removed in the 3 patients. In two patients, with short segment BE (SSBE) (≤ 3 cm), the metaplastic tissue was completely excised. A 2 cm circumferential EMR was performed in one patient with a polyp involving the whole EGJ. A simultaneous EMR-C of a BE-associated polypoid dysplastic lesion measuring 1 cm × 10 cm, was also carried out. In the two patients, histologic assessment detected LGD in BE. No complications occurred. Complete neosquamous re-epithelialization occurred in the two patients with SSBE. An esophageal recurrence occurred in the remaining one and was successfully retreated by EMR. Conclusion: EMR-C appears to be a safe and effective method for treating benign esophageal mucosal lesions, allowing also the complete removal of SSBE.

Original languageEnglish
Pages (from-to)5699-5704
Number of pages6
JournalWorld Journal of Gastroenterology
Volume12
Issue number35
Publication statusPublished - Sep 21 2006

Keywords

  • Barrett's esophagus
  • Endoscopic mucosal resection
  • Hyperplastic polyps

ASJC Scopus subject areas

  • Gastroenterology

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    De Ceglie, A., Lapertosa, G., Blanchi, S., Di Muzio, M., Picasso, M., Filiberti, R., Scotto, F., & Conio, M. (2006). Endoscopic mucosal resection of large hyperplastic polyps in 3 patients with Barrett's esophagus. World Journal of Gastroenterology, 12(35), 5699-5704.