Endoscopic papillary large balloon dilation in patients with large biliary stones and periampullary diverticula: Results of a multicentric series

Claudio Zulli, Giuseppe Grande, Gian Eugenio Tontini, Orazio Labianca, Girolamo Geraci, Carmelo Sciumè, Pavlos Antypas, Fausto Fiocca, Gianpiero Manes, Massimo Devani, Raffaele Manta, Attilio Maurano

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Introduction: Stone extraction represents the most frequent indication for endoscopic retrograde cholangiopancreatography (ERCP). Endoscopic papillary large balloon dilation (EPLBD) is a recent introduced approach consisting of an endoscopic papillary large balloon dilation following limited endoscopic sphyncterotomy (ES), which has been proven to be safe and effective for extraction of large common bile duct (CBD) stones. Peri-ampullary diverticula (PAD) are described in 10–20% of patients undergoing ERCP. Aim of our study is to evaluate efficacy and safety of EPLBD for the extraction of large biliary stones in patients with PAD. Methods: The prospectively collected endoscopy databases of 4 Italian ERCP high-volume centers were reviewed retrospectively, and all consecutive patients with an instrumental diagnosis of large biliary stones and PAD, between September 2014 and October 2016, were included in this study. Results: Eighty-one patients (36 males, median age 75 years) were treated between September 2014 and October 2016. Deep biliary cannulation was reached in 78/80 patients. Successful extraction was achieved in 74/78 patients at the first attempt. AEs occurred in 8 patients (1 severe). Younger age, stone size and incomplete stone extraction were significantly associated with AEs. Conclusions: EPLBD is an effective and safe technique in patients with PAD and large biliary stones, which avoids the need of other techniques, thereby reducing the risks of adverse events.

Original languageEnglish
Pages (from-to)828-832
JournalDigestive and Liver Disease
Volume50
Issue number8
DOIs
Publication statusPublished - 2018

Fingerprint

Diverticulum
Dilatation
Endoscopic Retrograde Cholangiopancreatography
Common Bile Duct
Catheterization
Endoscopy
Databases
Safety

Keywords

  • DASE
  • Difficult choledocholithiasis
  • Dilation assisted stone extraction
  • Endoscopic papillary large balloon dilation
  • EPLBD
  • Large bile duct stone
  • Therapeutic ERCP

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Endoscopic papillary large balloon dilation in patients with large biliary stones and periampullary diverticula : Results of a multicentric series. / Zulli, Claudio; Grande, Giuseppe; Tontini, Gian Eugenio; Labianca, Orazio; Geraci, Girolamo; Sciumè, Carmelo; Antypas, Pavlos; Fiocca, Fausto; Manes, Gianpiero; Devani, Massimo; Manta, Raffaele; Maurano, Attilio.

In: Digestive and Liver Disease, Vol. 50, No. 8, 2018, p. 828-832.

Research output: Contribution to journalArticle

Zulli, C, Grande, G, Tontini, GE, Labianca, O, Geraci, G, Sciumè, C, Antypas, P, Fiocca, F, Manes, G, Devani, M, Manta, R & Maurano, A 2018, 'Endoscopic papillary large balloon dilation in patients with large biliary stones and periampullary diverticula: Results of a multicentric series', Digestive and Liver Disease, vol. 50, no. 8, pp. 828-832. https://doi.org/10.1016/j.dld.2018.03.034
Zulli, Claudio ; Grande, Giuseppe ; Tontini, Gian Eugenio ; Labianca, Orazio ; Geraci, Girolamo ; Sciumè, Carmelo ; Antypas, Pavlos ; Fiocca, Fausto ; Manes, Gianpiero ; Devani, Massimo ; Manta, Raffaele ; Maurano, Attilio. / Endoscopic papillary large balloon dilation in patients with large biliary stones and periampullary diverticula : Results of a multicentric series. In: Digestive and Liver Disease. 2018 ; Vol. 50, No. 8. pp. 828-832.
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AU - Zulli, Claudio

AU - Grande, Giuseppe

AU - Tontini, Gian Eugenio

AU - Labianca, Orazio

AU - Geraci, Girolamo

AU - Sciumè, Carmelo

AU - Antypas, Pavlos

AU - Fiocca, Fausto

AU - Manes, Gianpiero

AU - Devani, Massimo

AU - Manta, Raffaele

AU - Maurano, Attilio

PY - 2018

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N2 - Introduction: Stone extraction represents the most frequent indication for endoscopic retrograde cholangiopancreatography (ERCP). Endoscopic papillary large balloon dilation (EPLBD) is a recent introduced approach consisting of an endoscopic papillary large balloon dilation following limited endoscopic sphyncterotomy (ES), which has been proven to be safe and effective for extraction of large common bile duct (CBD) stones. Peri-ampullary diverticula (PAD) are described in 10–20% of patients undergoing ERCP. Aim of our study is to evaluate efficacy and safety of EPLBD for the extraction of large biliary stones in patients with PAD. Methods: The prospectively collected endoscopy databases of 4 Italian ERCP high-volume centers were reviewed retrospectively, and all consecutive patients with an instrumental diagnosis of large biliary stones and PAD, between September 2014 and October 2016, were included in this study. Results: Eighty-one patients (36 males, median age 75 years) were treated between September 2014 and October 2016. Deep biliary cannulation was reached in 78/80 patients. Successful extraction was achieved in 74/78 patients at the first attempt. AEs occurred in 8 patients (1 severe). Younger age, stone size and incomplete stone extraction were significantly associated with AEs. Conclusions: EPLBD is an effective and safe technique in patients with PAD and large biliary stones, which avoids the need of other techniques, thereby reducing the risks of adverse events.

AB - Introduction: Stone extraction represents the most frequent indication for endoscopic retrograde cholangiopancreatography (ERCP). Endoscopic papillary large balloon dilation (EPLBD) is a recent introduced approach consisting of an endoscopic papillary large balloon dilation following limited endoscopic sphyncterotomy (ES), which has been proven to be safe and effective for extraction of large common bile duct (CBD) stones. Peri-ampullary diverticula (PAD) are described in 10–20% of patients undergoing ERCP. Aim of our study is to evaluate efficacy and safety of EPLBD for the extraction of large biliary stones in patients with PAD. Methods: The prospectively collected endoscopy databases of 4 Italian ERCP high-volume centers were reviewed retrospectively, and all consecutive patients with an instrumental diagnosis of large biliary stones and PAD, between September 2014 and October 2016, were included in this study. Results: Eighty-one patients (36 males, median age 75 years) were treated between September 2014 and October 2016. Deep biliary cannulation was reached in 78/80 patients. Successful extraction was achieved in 74/78 patients at the first attempt. AEs occurred in 8 patients (1 severe). Younger age, stone size and incomplete stone extraction were significantly associated with AEs. Conclusions: EPLBD is an effective and safe technique in patients with PAD and large biliary stones, which avoids the need of other techniques, thereby reducing the risks of adverse events.

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KW - Endoscopic papillary large balloon dilation

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