Endoscopic repair of cerebrospinal fluid rhinorrhea: Learning from our failures

P. Castelnuovo, S. Mauri, D. Locatelli, E. Emanuelli, G. Delù, G. Di Giulio

Research output: Contribution to journalArticlepeer-review


Endoscopic repair of cerebrospinal fluid (CSF) rhinorrhea is becoming a common procedure. The purpose of this study was to perform a literature analysis centering cases of treatment failure and to review our 31 cases with a 1-year minimum follow-up. An extensive search of the literature was conducted, which focused on success rate, follow-up, diagnostic techniques, graft material used, failure rate, and comments on failures. A retrospective analysis of our 31 patients was carried out, and all cases were treated with the endoscopic approach with a 1-year minimum follow-up. From the literature analysis, the median success rate at the first endoscopic attempt is 90%. Our success rate was 87.1%. Failures were analyzed. A unique protocol for CSF leak diagnosis does not exist; we suggest our diagnostic algorithm. Graft material used depends on the authors' experience, and based on this review of cases to date, did not significantly influence the success rate. The analysis of cases of failure shows that the majority of authors omit details. More research is needed to improve prevention of failures.

Original languageEnglish
Pages (from-to)333-342
Number of pages10
JournalAmerican Journal of Rhinology
Issue number5
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Otorhinolaryngology


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