La sorveglianza endoscopica delle IBD

Bowel cancer is an accepted but feared complication of chronic Inflammatory Bowel Disease (IBD). Despite differences, the increased risk of colorectal CRC in IBD has been accepted and has therefore led to expert opinion-based prevention guidelines that emphasize screening and surveillance colonoscopic examinations with random and targeted biopsies looking for precancerous dysplasia or early-stage cancers that would allow for preventative or curative surgical interventions. However, a major challenge in the diagnosis and prevention strategies of CRC in IBD is the accurate identification of dysplasia both by endoscopists and by pathologists. Although there has not been debate about the approach to high-grade dysplasia (HGD), colectomy for low-grade dysplasia (LGD) remains controversial in some centers and more information about the implications and natural history of LGD has been requested.