Abstract
Purpose: We investigated the effectiveness of dextranomer/hyaluronic acid copolymer (dextranomer microspheres in sodium hyaluronan solution) as a treatment for urinary incontinence due to sphincter incompetence in children and adolescents. Materials and Methods: Patients with urinary incontinence due to neurogenic and structural causes were given a transurethral injection of dextranomer/hyaluronic acid copolymer to increase bladder outlet resistance. Patients were assessed at 1, 3, 6, 12 and 24 months after injection using a validated questionnaire, 1-hour pad test, ultrasonography, cystography and cystometry. Patients who remained incontinent were offered repeat injections of dextranomer/hyaluronic acid copolymer up to a maximum of 3 injections. Results: A total of 16 patients 8 to 22 years old were treated with dextranomer/hyaluronic acid copolymer, including 3 with neurogenic bladder, 8 with bladder exstrophy after 3-stage reconstruction, 4 with penopubic epispadias and 1 with urogenital sinus. Mean volume injected was 2.8 ml. (range 1.8 to 4.0) and mean number of injections received was 2.3 per patient. Dry time interval increased by 43 minutes (p
| Original language | English |
|---|---|
| Pages (from-to) | 1868-1871 |
| Number of pages | 4 |
| Journal | Journal of Urology |
| Volume | 168 |
| Issue number | 4 II |
| Publication status | Published - Oct 2002 |
Fingerprint
Keywords
- Dextrans
- Endoscopy
- Hyaluronic acid
- Urinary incontinence
ASJC Scopus subject areas
- Urology
Cite this
Endoscopic treatment of urinary incontinence in pediatric patients : 2-Year experience with dextranomer/hyaluronic acid copolymer. / Caione, Paolo; Capozza, Nicola.
In: Journal of Urology, Vol. 168, No. 4 II, 10.2002, p. 1868-1871.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Endoscopic treatment of urinary incontinence in pediatric patients
T2 - 2-Year experience with dextranomer/hyaluronic acid copolymer
AU - Caione, Paolo
AU - Capozza, Nicola
PY - 2002/10
Y1 - 2002/10
N2 - Purpose: We investigated the effectiveness of dextranomer/hyaluronic acid copolymer (dextranomer microspheres in sodium hyaluronan solution) as a treatment for urinary incontinence due to sphincter incompetence in children and adolescents. Materials and Methods: Patients with urinary incontinence due to neurogenic and structural causes were given a transurethral injection of dextranomer/hyaluronic acid copolymer to increase bladder outlet resistance. Patients were assessed at 1, 3, 6, 12 and 24 months after injection using a validated questionnaire, 1-hour pad test, ultrasonography, cystography and cystometry. Patients who remained incontinent were offered repeat injections of dextranomer/hyaluronic acid copolymer up to a maximum of 3 injections. Results: A total of 16 patients 8 to 22 years old were treated with dextranomer/hyaluronic acid copolymer, including 3 with neurogenic bladder, 8 with bladder exstrophy after 3-stage reconstruction, 4 with penopubic epispadias and 1 with urogenital sinus. Mean volume injected was 2.8 ml. (range 1.8 to 4.0) and mean number of injections received was 2.3 per patient. Dry time interval increased by 43 minutes (p
AB - Purpose: We investigated the effectiveness of dextranomer/hyaluronic acid copolymer (dextranomer microspheres in sodium hyaluronan solution) as a treatment for urinary incontinence due to sphincter incompetence in children and adolescents. Materials and Methods: Patients with urinary incontinence due to neurogenic and structural causes were given a transurethral injection of dextranomer/hyaluronic acid copolymer to increase bladder outlet resistance. Patients were assessed at 1, 3, 6, 12 and 24 months after injection using a validated questionnaire, 1-hour pad test, ultrasonography, cystography and cystometry. Patients who remained incontinent were offered repeat injections of dextranomer/hyaluronic acid copolymer up to a maximum of 3 injections. Results: A total of 16 patients 8 to 22 years old were treated with dextranomer/hyaluronic acid copolymer, including 3 with neurogenic bladder, 8 with bladder exstrophy after 3-stage reconstruction, 4 with penopubic epispadias and 1 with urogenital sinus. Mean volume injected was 2.8 ml. (range 1.8 to 4.0) and mean number of injections received was 2.3 per patient. Dry time interval increased by 43 minutes (p
KW - Dextrans
KW - Endoscopy
KW - Hyaluronic acid
KW - Urinary incontinence
UR - http://www.scopus.com/inward/record.url?scp=0036783574&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036783574&partnerID=8YFLogxK
M3 - Article
VL - 168
SP - 1868
EP - 1871
JO - Journal of Urology
JF - Journal of Urology
SN - 0022-5347
IS - 4 II
ER -