TY - JOUR
T1 - Endothelial dysfunction evaluated by flow mediated dilation is strongly associated to metabolic syndrome in the elderly
AU - De Matthaeis, Angela
AU - Greco, Antonio
AU - Serviddio, Gaetano
AU - Stramaglia, Giovanna
AU - Vendemiale, Gianluigi
PY - 2010/8
Y1 - 2010/8
N2 - This study was carried out to assess whether endothelial dysfunction, evaluated by flow-mediated dilation (FMD), is related to the occurrence of the Metabolic Syndrome (MetS) in old age. Eighty patients (25 men and 55 women), mean age 74.1±7.4 years (range 65-99 yrs) were studied. Information on all subjects, medical history and regular medications was obtained. Subjects underwent a clinical examination and laboratory tests. The presence of MetS was evaluated according to the revised NCEP-ATP III criteria. An ultrasound vascular examination (US) of the carotid and brachial arteries was performed in all patients. Intima-media thickness (IMT), presence of plaques (PL), endothelium-dependent (EDV) and -independent vasodilation (EIDV) were also evaluated. Patients were divided into two groups according to the presence/absence of MetS. Significant differences were found between MetS and non MetS patients in: EDV (p
AB - This study was carried out to assess whether endothelial dysfunction, evaluated by flow-mediated dilation (FMD), is related to the occurrence of the Metabolic Syndrome (MetS) in old age. Eighty patients (25 men and 55 women), mean age 74.1±7.4 years (range 65-99 yrs) were studied. Information on all subjects, medical history and regular medications was obtained. Subjects underwent a clinical examination and laboratory tests. The presence of MetS was evaluated according to the revised NCEP-ATP III criteria. An ultrasound vascular examination (US) of the carotid and brachial arteries was performed in all patients. Intima-media thickness (IMT), presence of plaques (PL), endothelium-dependent (EDV) and -independent vasodilation (EIDV) were also evaluated. Patients were divided into two groups according to the presence/absence of MetS. Significant differences were found between MetS and non MetS patients in: EDV (p
KW - Elderly
KW - Endothelial dysfunction
KW - Flow mediated dilation
KW - Metabolic syndrome
UR - http://www.scopus.com/inward/record.url?scp=78751694353&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78751694353&partnerID=8YFLogxK
U2 - 10.3275/6707
DO - 10.3275/6707
M3 - Article
C2 - 19966538
AN - SCOPUS:78751694353
VL - 22
SP - 303
EP - 307
JO - Aging clinical and experimental research
JF - Aging clinical and experimental research
SN - 1594-0667
IS - 4
ER -